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2 -OTBDMS-C Ac

Price 3800 INR/ Kilograms

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MOQ : 25 Grams

2 -OTBDMS-C Ac Specification

Ingredients
2-(tert-Butyldimethylsilyloxy)acetyl chloride

Molecular Weight
208.76 g/mol

HS Code
29310099

Shelf Life
2 years under recommended conditions

Physical Form
Liquid

Grade
Laboratory Grade

Product Type
Organic Intermediate

Structural Formula
(CH3)3C-Si(CH3)2-O-CH2COCl

Shape
Amorphous

Smell
Mild, characteristic

Application
Used as a reagent for organic synthesis, pharmaceutical intermediates, and protecting group chemistry

Melting Point
Not applicable (liquid at RT)

EINECS No
None allocated

Solubility
Soluble in organic solvents (dichloromethane, ether, THF)

Storage
Store in a cool, dry place. Keep container tightly closed and under inert atmosphere.

Appearance
Clear colorless to pale yellow liquid

CAS No
175865-48-0

Properties
Organosilicon compound, reagent for organic synthesis, stable under ambient conditions

Poisonous
Yes (corrosive, handle with care)

Usage
Used in the synthesis of silyl-protected carboxylic acids and other derivatives

Density
1.015 Gram per cubic centimeter(g/cm3)

Purity
98%

Refractive Rate
n20/D 1.4321.438

Molecular Formula
C8H17ClO2Si

Compatibility
Avoid strong oxidizing agents, moisture

Hazard Statement
Causes burns to skin and eyes

Precautionary Measures
Wear gloves, goggles, and appropriate protective clothing

Flash Point
>85°C

Stability
Stable under recommended storage conditions

Boiling Point
78-80°C (at 5 mmHg)

Handling
Handle only in a chemical fume hood

UN Number
UN 3261

Transport Information
Corrosive, Class 8

Packaging Details
Sealed bottle, typically 25g, 100g

2 -OTBDMS-C Ac Trade Information

Minimum Order Quantity
25 Grams

Supply Ability
100 Grams Per Week

Delivery Time
1 Week

Main Export Market(s)
Eastern Europe, Western Europe, Middle East, Africa, South America, Asia, Central America, North America, Australia

Main Domestic Market
All India

About 2 -OTBDMS-C Ac

2 -OTBDMS-C Ac

CAS No : [121058-85-3]

M.Wt. 701.88

M.F. C38H47N3O8Si

Specification :

*Appearance: White to Off white powder,

*HPLC Purity: NLT 98%

*5'-ODMT-2'-OTBDMS Uridine (3'-Isomer): NMT 0.3%

*Residual Solvent: NMT 3.0%

*Moisture content by KF: NMT 1.0%

*1H NMR (Solvent : DMSO d6): Conforms with Structure

*LCMS: Corresponds to Mass

*APHA Test in 0.2M in DMSO: NMT 250

*Solubility: 0.2M in MDC

Key Features and Properties

2-OTBDMS-C Ac is an organosilicon compound prized for its stability and versatility in laboratory syntheses. With a high purity and a mild, characteristic smell, this reagent is supplied as an amorphous liquid. Its excellent solubility in common organic solvents like ether, dichloromethane, and THF allows seamless integration into diverse organic pathways, especially in the manipulation of silyl-protected carboxylic acids.

Safe Handling and Storage

Careful handling is mandatory when working with 2-OTBDMS-C Ac due to its corrosive nature. Always handle in a chemical fume hood and wear gloves, goggles, and protective clothing. The compound must be stored in tightly sealed bottles, placed in a cool, dry place, and under an inert atmosphere to ensure both product stability and user safety. Avoid contact with moisture or strong oxidizers.

Applications in Synthesis

This compound is widely used as a reagent for organic synthesis, particularly in the creation of silyl-protected carboxylic acids and other intermediates important to pharmaceuticals and advanced organic chemistry. Its robust stability and compatibility with standard laboratory conditions make it a favorite among research professionals seeking efficiency and precision in complex chemical transformations.

FAQ's of 2 -OTBDMS-C Ac:

Q: How should 2-OTBDMS-C Ac be safely handled during laboratory use?

A: Always handle 2-OTBDMS-C Ac in a well-ventilated chemical fume hood using gloves, goggles, and suitable protective clothing. Due to its corrosive properties, direct contact with skin or eyes can cause burns, so all safety protocols must be strictly followed.

Q: What are the recommended storage conditions for this reagent?

A: Store 2-OTBDMS-C Ac in a sealed bottle under an inert atmosphere. Keep the container in a cool, dry location, away from moisture and strong oxidizing agents. Proper storage preserves its stability and extends its shelf life up to two years.

Q: Where is 2-OTBDMS-C Ac commonly applied in organic synthesis?

A: This reagent is primarily used in laboratories and research facilities for synthesizing silyl-protected carboxylic acids and various pharmaceutical intermediates. Its ability to introduce silyl-protecting groups makes it valuable in complex molecule construction.

Q: What is the benefit of using 2-OTBDMS-C Ac in organic chemistry?

A: The main advantage lies in its efficient incorporation of tert-butyldimethylsilyl groups, which protect reactive sites during multi-step syntheses. This enhances reaction selectivity and improves overall laboratory workflow for complex organic syntheses.

Q: When is 2-OTBDMS-C Ac typically used in the synthesis process?

A: It is most often introduced during the protection step of carboxylic acids, where functional groups require temporary masking to prevent unwanted reactions in subsequent steps. Its stability allows it to perform effectively under standard synthesis conditions.

Q: What precautions should be taken in case of accidental exposure?

A: In the event of skin or eye contact, immediately rinse the affected area with plenty of water for at least 15 minutes and seek medical attention. Remove contaminated clothing and ensure the area is well-ventilated. Refer to safety data for further guidance.

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