About Vinyl Magnesium Bromide
Vinyl Magnesium Bromide
CAS No.: n1826-67-1
Molecular Formula : C2H3BrMg
Formula Weight : 131.25
Appearance : Clear light brown to brown solution
Density : 0.981 g/mL at 25C
Fp : 1F
High-Performance Vinylation AgentVinyl Magnesium Bromide is an essential tool for synthetic chemists, particularly in pharmaceutical, agrochemical, and specialty chemical synthesis. Its high reactivity enables the efficient introduction of vinyl groups into various substrates, supporting the creation of complex molecular architectures.
Safe Handling and StorageThis reagent is highly flammable and reacts violently with moisture and air, producing toxic and corrosive byproducts. Proper storage under inert gas, such as argon or nitrogen, and strict adherence to safety protocols are crucial to minimize risks and maintain product integrity.
Applications Across IndustriesPrimarily used as a nucleophile or Grignard reagent, Vinyl Magnesium Bromide is a valuable intermediate for manufacturers, exporters, and researchers. Its application ranges from academic research to industrial-scale processes, supporting innovation in multiple sectors throughout India and globally.
FAQs of Vinyl Magnesium Bromide:
Q: How should Vinyl Magnesium Bromide solution be stored safely?
A: Vinyl Magnesium Bromide should be stored in sealed glass bottles under an inert gas atmosphere, such as argon or nitrogen, at temperatures below 30C. Its crucial to protect the reagent from moisture and air to prevent hazardous decomposition and ensure product longevity.
Q: What are the primary applications of Vinyl Magnesium Bromide in organic synthesis?
A: This reagent is predominantly used for vinylation reactions, where it introduces a vinyl group into carbonyl or other electrophilic substrates. Such transformations are valuable in the synthesis of pharmaceuticals, agrochemicals, and specialty chemicals.
Q: When is it appropriate to use Vinyl Magnesium Bromide as a Grignard reagent?
A: Vinyl Magnesium Bromide is suitable for use whenever the vinyl group needs to be directly attached to electrophilic centers, particularly carbonyl compounds. It is commonly chosen when a strong nucleophile with high selectivity is required in laboratory or industrial settings.
Q: Where can Vinyl Magnesium Bromide solution be procured in India?
A: Vinyl Magnesium Bromide is available through chemical distributors, suppliers, manufacturers, exporters, and retailers throughout India in various volumes (100 mL, 500 mL, 1 L), typically packaged under argon in glass bottles.
Q: What safety precautions should be followed when handling Vinyl Magnesium Bromide?
A: Personal protective equipment is essential, including gloves, goggles, and chemical-resistant clothing. Work in a well-ventilated fume hood, avoid exposure to moisture or air, keep away from ignition sources, and handle exclusively with suitable dry apparatus.
Q: How does using Vinyl Magnesium Bromide benefit organic synthesis processes?
A: Its high reactivity and strong nucleophilicity enable efficient vinyl group transfers, supporting the rapid construction of complex molecules, which enhances yield and selectivity in sophisticated synthetic pathways.