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Croscarmellose Sodium

Price 4100 INR/ Kilograms

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MOQ : 1 Kilograms

Croscarmellose Sodium Specification

Solubility
Insoluble in water, swells substantially in water

Shape
Amorphous

Storage
Store in a cool, dry place away from moisture

Shelf Life
36 months

Molecular Weight
Approximately 994.4 g/mol

Melting Point
Decomposes before melting

EINECS No
277-098-7

Usage
Used as a superdisintegrant in tablet formulations

Physical Form
Powder

Density
0.60 Gram per cubic centimeter(g/cm3)

HS Code
39123100

Ph Level
5.0 - 7.0 (1% solution)

Ingredients
Crosslinked Carboxymethylcellulose Sodium

CAS No
74811-65-7

Product Type
Pharmaceutical Raw Material

Smell
Odorless

Properties
Superdisintegrant; facilitates tablet dissolution

Application
Pharmaceuticals, nutraceuticals, food industry

Poisonous
NO

Structural Formula
Cross-linked carboxymethyl cellulose sodium structure

Appearance
White to off-white powder

Purity
>98%

Taste
Tasteless

Grade
Pharma Grade

Molecular Formula
C20H24Na2O19

Croscarmellose Sodium Trade Information

Minimum Order Quantity
1 Kilograms

Supply Ability
1 Kilograms Per Week

Delivery Time
1 Week

About Croscarmellose Sodium

Crosscarmellose Sodium

Other Name : Sodium CarboxyMethtylCellulose
CAS Number : 74811-65-7
Molecular Formula : C12H10CA3O14.4H20
Application : Used as Disintegrant in Capsules, Tablet and Granule Formulations.

Superdisintegrant for Enhanced Tablet Performance

Croscarmellose Sodium dramatically improves the dissolution and bioavailability of active pharmaceutical ingredients in tablets. Its crosslinked structure allows for exceptional swelling properties when exposed to moisture, ensuring tablets disintegrate rapidly upon ingestion for optimal therapeutic effect. This makes it a preferred choice among formulators for fast-acting and reliable oral dosage forms.

Strict Quality and Safety Standards

Every batch complies with pharmaceutical-grade requirements: bulk density of 0.450.55 g/cm, residue on ignition of 8.010.0%, and stringent microbial limits. It is tasteless, odorless, and non-poisonous, making it safe for use in oral solid dosage forms. Sourced, manufactured, and supplied by trusted distributors and exporters in India, the product conforms to CAS No: 74811-65-7 and EINECS No: 277-098-7.

Applications in Diverse Industries

Beyond pharmaceuticals, Croscarmellose Sodium is utilized in nutraceuticals and the food industry as a functional excipient. Its grade, purity, and safety profile make it suitable for bulk supply, supporting manufacturers, traders, wholesalers, and retailers who demand consistent quality for their end products.

FAQs of Croscarmellose Sodium:

Q: How does Croscarmellose Sodium act as a superdisintegrant in tablet formulations?

A: Croscarmellose Sodium, due to its crosslinked structure, swells rapidly upon contact with water or gastrointestinal fluids. This swelling action helps break tablets apart, promoting quick dispersion and dissolution, which leads to faster onset of the tablets intended action.

Q: What are the specific quality standards for Croscarmellose Sodium?

A: It must meet key pharmaceutical standards: loss on drying not exceeding 10%, pH between 5.0 and 7.0 (for a 1% solution), bulk density of 0.450.55 g/cm, purity above 98%, heavy metals below 10 ppm, and strict microbial limits. Residue on ignition should be between 8.010.0% and most particles (85%) pass through an 80 mesh sieve.

Q: Where is Croscarmellose Sodium commonly applied?

A: Its primary application is in pharmaceutical tablet and capsule manufacturing as a superdisintegrant. However, it also finds use in nutraceutical and food industries due to its safety, functionality, and compliance with relevant quality standards.

Q: What is the recommended process for storing Croscarmellose Sodium?

A: It should be stored in a cool, dry place away from moisture and direct sunlight to preserve its physical and chemical properties. When stored properly, Croscarmellose Sodium maintains its efficiency and safety profile for up to 36 months.

Q: When should Croscarmellose Sodium be used in tablet formulations?

A: It is best used when rapid tablet disintegration and immediate drug release are desired. This is essential for formulations where a fast onset of action is of therapeutic importance.

Q: What are the benefits of choosing pharma-grade Croscarmellose Sodium?

A: Pharma-grade Croscarmellose Sodium ensures consistency in performance, meets international safety and quality benchmarks, and reduces risks of contaminationcrucial for regulated industries like pharmaceuticals and nutraceuticals.

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