About 2-Diethylaminoethyl chloride hydrochloride
2-Diethylaminoethyl chloride hydrochloride
CAS No.: 869-24-9
Formula: (C2H5)2NCH2CH2Cl HCl
Molecular Weight: 172.10
Appearance: White to off-white powder
Solubility: hygroscopic
Melting Point: 208-212 C(lit.)
Assay: 98.0% Min.
Versatile Intermediate for Synthesis2-Diethylaminoethyl chloride hydrochloride is prized for its role as an intermediate in synthesizing a range of pharmaceutical compounds, especially antihistamines and local anesthetics. Its reactivity makes it essential in organic chemistry labs for preparing quaternary ammonium compounds. Widely used in the pharmaceutical, analytical, and industrial sectors, this compound ensures high performance and purity for advanced applications.
Safe Handling and Storage GuidelinesDue to its corrosive and toxic nature, handling requires protective equipment including gloves, goggles, and fume hood operation. Store in tightly sealed containers, away from moisture, in a cool, dry, and well-ventilated place to maintain stability and extend shelf life. Adhering to these recommendations reduces exposure risks and preserves the compounds integrity for up to two years.
FAQs of 2-Diethylaminoethyl chloride hydrochloride:
Q: What are the main applications of 2-Diethylaminoethyl chloride hydrochloride?
A: This compound is primarily used as an intermediate in the synthesis of pharmaceuticals, such as antihistamines and local anesthetics, and for producing quaternary ammonium compounds. It is also used in various organic synthesis processes within the pharmaceutical and chemical industries.
Q: How should 2-Diethylaminoethyl chloride hydrochloride be handled safely?
A: Always handle this compound under a fume hood, using appropriate protective gloves, goggles, and other personal protective equipment (PPE), as it is corrosive, toxic, and can be harmful if inhaled or ingested. Avoid contact with skin, eyes, and clothing.
Q: When is it necessary to take extra precautions with this substance?
A: Take extra precautions during handling, weighing, and transferring the compound, especially since it is highly hygroscopic and reacts readily with water and moisture in the air. Immediately clean spills and prevent any contact with incompatible materials.
Q: Where should 2-Diethylaminoethyl chloride hydrochloride be stored for optimal stability?
A: Store the compound in tightly sealed containers, in a cool, dry, well-ventilated area, protected from moisture. Proper storage maintains purity and ensures a shelf life of 1224 months.
Q: What are the benefits of using this compound in pharmaceutical synthesis?
A: Its high purity and reactivity facilitate efficient and selective synthesis of pharmaceutical intermediates, resulting in higher yields and superior final product quality, crucial for medical and industrial applications.
Q: How is 2-Diethylaminoethyl chloride hydrochloride typically transported and packaged?
A: It is transported and regulated as a hazardous material (UN2810) and normally packaged in fibre drums or HDPE drums to prevent contamination and moisture ingress during shipping.