About P-Toluene Sulfonyl Chloride (PTSC)
P-Toluene Sulfonyl Chloride (PTSC)
CAS No.: 98-59-9
Formula : C7H7CLO2S
Appearance : White Crystalline Powder
Purity : 99% min
Melting Point : 67°C min
Water : 0.1% max
Colority (APHA) : 20 Pt/Co max
OTSC (o-toluene sulfonyl chloride) : 0.2% max
Free Acid : 0.3% max
Application : It can be used for organic synthesis, for example: dyes, saccharin, etc.
Key Features and CompositionPTSC is a highly pure (GC >99%) powder or crystalline solid, characterized by a specific gravity of 1.32 and a melting point of 69-71C. It possesses a pungent smell and reacts with water, making careful handling crucial. The chemical is supplied with technical or laboratory grade quality, suitable for a range of industrial and research applications.
Applications in Industry and ResearchP-Toluene Sulfonyl Chloride serves as a vital reagent for sulfonylation processes in organic synthesis, protecting functional groups, and acting as a valuable intermediate in producing pharmaceuticals and dye compounds. Thanks to its high reactivity and purity, it is indispensable for chemists in both laboratory and industrial settings.
Safe Handling and Storage GuidelinesDue to its toxic and irritant properties, PTSC must be handled with protective gear, avoiding direct contact and inhalation. The compound remains stable when stored in a tightly closed container in a cool, dry, and well-ventilated area. It has a 24-month shelf life and is classified as hazardous goods (UN 2508) for transport.
FAQs of P-Toluene Sulfonyl Chloride (PTSC):
Q: How should P-Toluene Sulfonyl Chloride be safely stored and handled?
A: PTSC must be stored in tightly closed containers, in a cool, dry, well-ventilated area, away from moisture and incompatible substances. Always use appropriate protective gear, including gloves, goggles, and masks, to avoid skin contact or inhalation since the chemical can cause irritation and is toxic.
Q: What is the primary usage of P-Toluene Sulfonyl Chloride in industry?
A: PTSC is mainly used as a sulfonylation agent in organic synthesis, often serving as a protecting group. It is also crucial in manufacturing pharmaceuticals, dye intermediates, and various chemical compounds due to its high reactivity and purity.
Q: Where is PTSC typically supplied or distributed from?
A: P-Toluene Sulfonyl Chloride is manufactured, exported, imported, and supplied by companies in India. It is available through a range of channel partners, including distributors, exporters, retailers, and wholesalers, who can provide custom production quantities based on requirements.
Q: What are the physical and chemical properties of PTSC that affect its application?
A: PTSC is a crystalline white to off-white solid with a characteristic, pungent smell, melting point of 69-71C, and specific gravity of 1.32. It is slightly soluble in water and highly soluble in organic solvents, facilitating its use in various organic synthesis applications.
Q: When does PTSC decompose and what precautions are necessary during heating?
A: PTSC begins to decompose at its boiling point of 165C. It has a flash point above 110C, so heating should be conducted with care, employing appropriate safety measures to prevent decomposition and ensure safe handling.
Q: How does PTSC benefit organic synthesis processes?
A: PTSC enables efficient sulfonylation and acts as a reliable protecting group for functional groups in complex organic synthesis. Its high purity and consistent quality streamline reaction outcomes, making it indispensable for research and industrial production.