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5'-O-(4,4'-dimethoxytrityl) N4-Benzoyl-2'- deoxycytidine

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5'-O-(4,4'-dimethoxytrityl) N4-Benzoyl-2'- deoxycytidine

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5'-O-(4,4'-dimethoxytrityl) N4-Benzoyl-2'- deoxycytidine Specification

Storage
Store at -20C, in a dry and dark place, tightly sealed

Usage
Used as a protected nucleoside building block in automated DNA synthesis

Molecular Formula
C37H36N4O7

Appearance
White to off-white powder

Molecular Weight
648.71 g/mol

Melting Point
215218 C (decomposition)

Poisonous
Non-poisonous for lab handling

Properties
High purity, suitable for oligonucleotide synthesis, moisture sensitive

Purity
98% (HPLC)

Grade
Molecular Biology / Synthesis Grade

Shelf Life
At least 24 months if stored properly

Smell
Odorless or faint organic odor

Physical Form
Solid

Solubility
Soluble in acetonitrile, dichloromethane, DMF; slightly soluble in water

Taste
Not determined

Structural Formula
See product image or consult supplier documentation

Refractive Rate
Not determined

Ingredients
5-O-(4,4-dimethoxytrityl) N4-Benzoyl-2-deoxycytidine

Ph Level
Neutral (in solution, approx. pH 6.5-7.5)

Shape
Crystalline, powder form

Application
Oligonucleotide synthesis, DNA synthesis, laboratory research

CAS No
137330-36-2

Density
Gram per cubic centimeter(g/cm3)

HS Code
29349900

Product Type
Nucleoside Analog / DNA Synthesis Reagent

Storage Condition Details
Desiccate, protect from light, store under inert atmosphere

Regulatory Status
For research use only, not for human or animal consumption

Inchi Key
AXCUXQDJTPRPPZ-UHFFFAOYSA-N

Packaging
Supplied in sealed amber vials

Handling Precautions
Use under inert atmosphere. Avoid moisture contact and prolonged exposure to light.

Quality Assurance
HPLC and NMR tested for identity and purity

Synonyms
DMT-dC(Bz) Phosphoramidite precursor

Protecting Groups
5'-O-(4,4'-dimethoxytrityl), N4-Benzoyl

Transport Information
Non-hazardous for air, sea, and road transport

Chirality
Contains one chiral center at the 2' position

Sensitive to
Moisture, light

5'-O-(4,4'-dimethoxytrityl) N4-Benzoyl-2'- deoxycytidine Trade Information

Supply Ability
100 Per Week

Delivery Time
1 Week

Main Export Market(s)
Western Europe, Eastern Europe, Middle East, South America, Asia, Central America, North America, Australia, Africa

Main Domestic Market
All India

About 5'-O-(4,4'-dimethoxytrityl) N4-Benzoyl-2'- deoxycytidine

5'-O-(4,4'-dimethoxytrityl) N4-Benzoyl-2'- deoxycytidine

CAS No : [67219-55-0]

M.Wt. 633.7

M.F.C37H35N3O7

Specification :

*Appearance: White to Off White Powder

*Purity by HPLC (%Area): NLT 98.0%

*1H NMR (Solvent:DMSO d6): Conforms with structure

*LCMS: Corresponds to Mass

*Moisture Content (KF w/w): NMT 1.0%

*Residual Solvents (%w/w): NMT 3.0%

*APHA in 0.2M DMSO solution: NMT 300

*Solubility: 0.2M in DMF

Achieve Precision in DNA Synthesis

With its high purity and protective groups, DMT-dC(Bz) offers exceptional performance for oligonucleotide synthesis. The single chiral center and rigorous quality controls ensure consistent, reliable results in demanding nucleic acid research applications. Its stability and compatibility are ideal for automated DNA synthesis workflows.

Critical Storage and Handling Recommendations

Due to its moisture and light sensitivity, 5-O-(4,4-dimethoxytrityl) N4-Benzoyl-2-deoxycytidine should be stored in tightly sealed amber vials at -20C, in a dry, dark environment under an inert atmosphere. Strict adherence to these conditions preserves its activity and maximizes its shelf life, which can extend beyond 24 months.

FAQ's of 5'-O-(4,4'-dimethoxytrityl) N4-Benzoyl-2'- deoxycytidine:

Q: How should 5-O-(4,4-dimethoxytrityl) N4-Benzoyl-2-deoxycytidine be stored to maintain its stability?

A: For optimal stability, store the compound at -20C in a tightly sealed amber vial under dry, dark conditions. Protect it from moisture and light, and use an inert atmosphere such as nitrogen or argon when handling.

Q: What is the primary use of DMT-dC(Bz) in laboratory research?

A: DMT-dC(Bz) is utilized as a protected nucleoside building block for automated DNA and oligonucleotide synthesis. Its protective groups facilitate high-fidelity assembly of DNA sequences in research and molecular biology.

Q: When is it necessary to use DMT-dC(Bz) with its specific protecting groups?

A: The 5-O-(4,4-dimethoxytrityl) and N4-benzoyl protecting groups are crucial during the stepwise chemical synthesis of oligonucleotides, preventing undesired side reactions and ensuring efficient strand assembly.

Q: Where is this product typically supplied from, and who are the main users?

A: DMT-dC(Bz) is supplied by distributors, exporters, manufacturers, and wholesalers-primarily in India. It is used by laboratories specializing in molecular biology, genetic research, and nucleic acid synthesis.

Q: What precautions need to be taken while handling DMT-dC(Bz)?

A: Handle the compound under an inert atmosphere to prevent moisture uptake, and avoid prolonged exposure to light. Always keep it tightly sealed and use appropriate laboratory safety measures during use.

Q: How is the quality of DMT-dC(Bz) assured before delivery?

A: Each batch is tested by HPLC and NMR to confirm identity and purity levels (98%). The product is supplied in sealed amber vials to prevent contamination and degradation.

Q: What benefits does DMT-dC(Bz) offer in the DNA synthesis process?

A: Its high purity, robust protective groups, and precise chiral configuration contribute to accurate DNA strand assembly, reducing synthesis errors and improving overall yield in oligonucleotide production.

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