About Actidione
Actidione
Other Name : Cycloheximide
Molecular Formula : C15H23NO4
Molecular Weight(Mass): 281.35gm/mole
Appearance : White to off-white crystalline powder
Assay : 98%
Solubility : Soluble in chloroform, ether, acetone, methanol and ethanol
Melting range : 110-113C
Specific rotation [a] D/20 (C=2,water): +7 to +9
CAS Number : 66-81-9
Research Applications and UsesActidione serves primarily as a selective inhibitor for eukaryotic protein synthesis, making it a valuable tool in biochemical, microbiological, and antifungal research. Its ability to hinder cell growth is exploited in laboratory experiments to study protein function and synthesis, contributing significantly to advances in cell biology.
Safe Handling and Storage GuidelinesGiven its high toxicity, Actidione must be handled using appropriate personal protective equipment such as gloves, lab coats, and safety goggles. Avoid direct contact, inhalation, or ingestion. Store the compound in a cool, dry place, shielded from light, and ensure containers are tightly closed to preserve its stability and prevent contamination.
Ecological and Transport ConsiderationsActidione poses severe risks to aquatic life and should never be released into the environment. It must be transported under ambient temperature conditions with secure, tight containers, adhering strictly to the UN2811 guidelines and Packing Group II requirements for hazardous substances.
FAQs of Actidione:
Q: How is Actidione (Cycloheximide) commonly used in laboratory research?
A: Actidione is frequently utilized as a selective inhibitor of eukaryotic protein synthesis, aiding researchers in protein functional studies, antifungal testing, and various cell biology experiments.
Q: What precautions should be taken when handling pure Actidione?
A: Use personal protective equipment including gloves, safety goggles, and lab coats. Avoid direct contact, inhalation, or ingestion as Actidione is highly toxic and can cause severe health hazards if misused.
Q: When is it recommended to use Actidione in experiments?
A: Actidione should be employed during controlled biochemical and microbiological studies where inhibition of protein synthesis in eukaryotic cells is required, and when selective antifungal action is needed.
Q: Where should Actidione be stored to ensure its longevity?
A: Store Actidione in a cool, dry environment, away from direct light, with the container tightly sealed to maintain its purity and effectiveness over its two-year shelf life.
Q: What are the transport and ecological safety guidelines for Actidione?
A: Transport Actidione at ambient temperature in a tightly closed container, complying with UN2811 hazardous material protocols. Prevent any release into aquatic environments due to its long-lasting toxic impact on aquatic life.
Q: What benefits does Actidione offer in scientific research?
A: Actidione provides precise control over eukaryotic protein synthesis, facilitating advanced research in cell biology, biochemistry, and microbiology while enabling selective antifungal testing.