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5'-O-(4,4'-dimethoxytrityl) N4-Acetyl-2'- deoxycytidine

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5'-O-(4,4'-dimethoxytrityl) N4-Acetyl-2'- deoxycytidine

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5'-O-(4,4'-dimethoxytrityl) N4-Acetyl-2'- deoxycytidine Specification

Shelf Life
2 years when properly stored

Structural Formula
Refer image: https://cpimg.tistatic.com/6520578/s/4/5-O-44-dimethoxytrityl-N4-Acetyl-2-deoxycytidine.jpg

Ingredients
5-O-(4,4-dimethoxytrityl) N4-Acetyl-2-deoxycytidine

Molecular Weight
653.72 g/mol

Molecular Formula
C37H39N3O8

Smell
Odorless

HS Code
29349900

Properties
Protecting group for oligonucleotide synthesis, DMT and N4-Acetyl protected, high purity required for DNA/RNA synthesis.

Purity
>98%

Application
Oligonucleotide synthesis, nucleic acid research

Solubility
Soluble in DMF, DMSO, and common organic solvents

Appearance
White to off-white crystalline powder

Storage
Store at -20°C, protect from light and moisture

Melting Point
155-160°C

CAS No
87109-22-4

Physical Form
Solid

Taste
Not determined

Refractive Rate
Not determined

Shape
Crystalline

Density
Gram per cubic centimeter(g/cm3)

Poisonous
NO

Usage
Used as a protected nucleoside for automated DNA/RNA synthesis

Grade
Synthesis Grade

Product Type
Nucleoside Phosphoramidite Intermediate

Transport Info
Not regulated as a hazardous material

Handling
Use appropriate laboratory precautions; avoid moisture and light exposure

Storage Conditions
Tightly sealed, dry, and protected from light

Synonyms
DMT-dC(Ac), 5-O-(4,4-dimethoxytrityl)-N4-acetyl-2-deoxycytidine

Stability
Stable under recommended storage conditions

Hazard Statements
Not hazardous under normal laboratory usage

Packaging
Typically supplied in amber glass vials

5'-O-(4,4'-dimethoxytrityl) N4-Acetyl-2'- deoxycytidine Trade Information

Supply Ability
100 Per Week

Delivery Time
1 Week

Main Export Market(s)
Western Europe, Asia, Australia, North America, Eastern Europe, Middle East, Africa, Central America, South America

Main Domestic Market
All India

About 5'-O-(4,4'-dimethoxytrityl) N4-Acetyl-2'- deoxycytidine

5'-O-(4,4'-dimethoxytrityl) N4-Acetyl-2'- deoxycytidine

CAS No : [100898-63-3]

M.Wt. 571.62

M.F. C32H33N3O7

Specification :

*Appearance: White to Off White Powder

*Purity by HPLC (%Area): NLT 98.0%

*1H NMR (Solvent:DMSO d6): Conforms with structure

*LCMS: Corresponds to Mass

*Moisture Content (KF w/w): NMT 1.0%

*Residual Solvents (%w/w): NMT 3.0%

*APHA in 0.2M DMSO solution: NMT 300

*Solubility: 0.2M in DMF

Versatile Protecting Groups for Nucleic Acid Synthesis

The DMT and N4-acetyl groups play a crucial role in protecting reactive sites during nucleic acid synthesis, ensuring high fidelity and efficiency. Their robust stability minimizes side reactions, making 5-O-(4,4-dimethoxytrityl) N4-acetyl-2-deoxycytidine invaluable for precise automated DNA or RNA assembly in research and development laboratories.

Optimal Storage and Handling Guidelines

This product maintains stability when stored at -20C, sealed tightly and shielded from light and moisture. Amber glass vials are used for packaging to further protect against degradation. Ensuring these conditions are met maximizes shelf life and preserves compound purity, vital to consistent laboratory results.

FAQs of 5-O-(4,4-dimethoxytrityl) N4-Acetyl-2- deoxycytidine:

Q: How should 5-O-(4,4-dimethoxytrityl) N4-acetyl-2-deoxycytidine be handled in the laboratory?

A: Handle this compound using standard laboratory safety precautions, such as wearing gloves and protective eyewear. Avoid unnecessary exposure to moisture and light, as these can affect the compounds stability and integrity.

Q: What is the recommended storage condition for this protected nucleoside?

A: Store the product at -20C in a tightly sealed container, protected from moisture and light. The use of amber glass vials helps maintain its purity and extends shelf life up to two years.

Q: When is 5-O-(4,4-dimethoxytrityl) N4-acetyl-2-deoxycytidine commonly used in research settings?

A: It is primarily used during automated DNA and RNA synthesis as a protected building block, facilitating the incorporation of cytidine while preventing unwanted side reactions during chain assembly.

Q: Where can I purchase this product in India?

A: You can obtain 5-O-(4,4-dimethoxytrityl) N4-acetyl-2-deoxycytidine through various channels including distributors, exporters, importers, manufacturers, retailers, suppliers, traders, and wholesalers specialized in chemical reagents in India.

Q: What is the main benefit of using both DMT and N4-acetyl protecting groups?

A: Using these protecting groups ensures selective and reliable protection of reactive sites on the nucleoside, minimizing undesired modifications and enhancing yield and purity during oligonucleotide synthesis.

Q: How is this compound typically packaged and transported?

A: It is commonly supplied in amber glass vials to protect against light and moisture. The product is not regulated as hazardous material, simplifying its shipping and storage requirements.

Q: What applications does 5-O-(4,4-dimethoxytrityl) N4-acetyl-2-deoxycytidine support?

A: This compound is essential for oligonucleotide synthesis and nucleic acid research, providing a high-purity precursor for constructing DNA or RNA strands in academic and industrial laboratories.

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