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Ajmaline

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MOQ : 50 Kilograms

Ajmaline Specification

Smell
Odorless

Usage
Clinical, research, pharmaceutical synthesis

Ingredients
Ajmaline

Grade
Pharma Grade

Product Type
Pharmaceutical Intermediate / API

Application
Used in cardiac arrhythmia diagnosis and treatment

Melting Point
207-209C

Molecular Formula
C20H26N2O4

Shelf Life
2 years (when properly stored)

HS Code
29349900

Solubility
Soluble in ethanol, methanol; sparingly soluble in water

EINECS No
224-480-0

Taste
Bitter

Appearance
White crystalline powder

Molecular Weight
358.43 g/mol

Poisonous
Yes (pharmacologically active; handle with care)

Physical Form
Solid

Properties
Alkaloid, antiarrhythmic agent, crystalline solid

CAS No
4368-28-9

Purity
98%

Shape
Crystalline

Storage
Store in cool, dry place, protected from light

Structural Formula
Refer to chemical structure: C20H26N2O4

Packing Type
HDPE bottles or glass vials, as per requirement

Stability
Stable under recommended storage conditions

Bioavailability
Variable depending on route; subject to first-pass metabolism

Extraction Source
Rauwolfia serpentina (natural); may be produced synthetically

Route of Administration
Intravenous (IV) or oral

IUPAC Name
(5,12)-19,20-dihydro-3-ethyl-5,12-epoxy-8,14,17,19-tetrahydroindolo[2,3-a]quinolizine-17-carboxylic acid methyl ester

Regulatory Status
Subject to pharmaceutical regulatory approvals

Therapeutic Classification
Class I antiarrhythmic agent

Transport Information
Handle as dangerous goods. Avoid exposure to sunlight and heat during transit.

Hazard Statements
Use with caution. Toxic if ingested or in contact with skin in large doses.

Certificate of Analysis
Available upon request

Boiling Point
Not available (decomposes)

Quality Assurance
Complies with international pharmacopoeia standards

Toxicity
May cause bradycardia, hypotension, or other adverse cardiac effects at overdose

Ajmaline Trade Information

Minimum Order Quantity
50 Kilograms

Supply Ability
1 Kilograms Per Week

Delivery Time
1 Week

About Ajmaline

Ajmaline

Other Name : (17R,21)-ajmalan- 17,21-diol OR (1R,9R,10S,13R,14R,16S,18S)- 13-ethyl- 8-methyl- 8,15-diazahexacyclo [14.2.1.01,9.02,7.010,15.012,17] nonadeca- 2(7),3,5-triene- 14,18-diol

CAS Number : 4360-12-7

Molecular Formula : C20H26N2O2

Application : For use as an antiarrhythmic agent

High-Purity Pharmaceutical Grade Ajmaline

Ajmaline offered complies with international pharmacopoeia standards and is supplied as a white, crystalline powder intended for clinical, research, and pharmaceutical synthesis use. Packed in HDPE bottles or glass vials as per customer requirement, it is available from certified distributors, exporters, importers, manufacturers, and wholesalers in India. Each batch can be accompanied by a Certificate of Analysis upon request, assuring quality and traceability.

Storage and Handling Guidelines

Ajmaline should be stored in a cool, dry environment, away from light, to ensure its two-year shelf life and maintain stability. Since it is toxic in large doses, all handling must employ safety precautions to prevent ingestion, skin contact, and inhalation. During transport, Ajmaline is classified as dangerous goods and must be protected from direct sunlight and excess heat.

FAQs of Ajmaline:

Q: How is Ajmaline typically administered in clinical settings?

A: Ajmaline is usually administered either intravenously (IV) or orally, depending on the intended clinical application. The IV route is preferred for rapid action, especially in diagnosing or treating certain cardiac arrhythmias.

Q: What are the primary uses and benefits of Ajmaline?

A: Ajmaline is mainly used to diagnose and manage cardiac arrhythmias by stabilizing abnormal heart rhythms. Its rapid effect during IV administration is especially valuable for clinical diagnosis, including the confirmation of Brugada syndrome.

Q: When should Ajmaline be handled as a hazardous substance?

A: Ajmaline is considered hazardous and should be handled with caution at all times. It is toxic in large doses, may cause serious cardiac adverse effects, and requires appropriate protective measures during handling, transport, and storage.

Q: Where should Ajmaline be stored for optimal stability?

A: Store Ajmaline in a cool, dry place, protected from light, using its original container (HDPE bottle or glass vial). These conditions will help ensure its stability and full shelf life of up to two years.

Q: What is the process for obtaining a Certificate of Analysis for Ajmaline?

A: A Certificate of Analysis (CoA) can be provided upon request by the distributor or supplier. The CoA confirms the batch-specific quality, purity (98%), and compliance with international standards.

Q: How does the extraction source of Ajmaline affect its use?

A: Ajmaline can be extracted naturally from Rauwolfia serpentina or produced synthetically. Regardless of the source, it is subject to the same pharmaceutical standards for purity and efficacy.

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