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Ajmaline
Ajmaline

Ajmaline

MOQ : 50 Kilograms

Ajmaline Specification

  • Ingredients
  • Ajmaline
  • Properties
  • Alkaloid, antiarrhythmic agent, crystalline solid
  • Grade
  • Pharma Grade
  • Poisonous
  • Yes (pharmacologically active; handle with care)
  • Molecular Formula
  • C20H26N2O4
  • Structural Formula
  • Refer to chemical structure: C20H26N2O4
  • Usage
  • Clinical, research, pharmaceutical synthesis
  • HS Code
  • 29349900
  • Melting Point
  • 207-209C
  • Purity
  • 98%
  • Taste
  • Bitter
  • CAS No
  • 4368-28-9
  • Appearance
  • White crystalline powder
  • Shape
  • Crystalline
  • Shelf Life
  • 2 years (when properly stored)
  • Product Type
  • Pharmaceutical Intermediate / API
  • Solubility
  • Soluble in ethanol, methanol; sparingly soluble in water
  • Smell
  • Odorless
  • Molecular Weight
  • 358.43 g/mol
  • Application
  • Used in cardiac arrhythmia diagnosis and treatment
  • Physical Form
  • Solid
  • EINECS No
  • 224-480-0
  • Storage
  • Store in cool, dry place, protected from light
  • Route of Administration
  • Intravenous (IV) or oral
  • Boiling Point
  • Not available (decomposes)
  • Extraction Source
  • Rauwolfia serpentina (natural); may be produced synthetically
  • Transport Information
  • Handle as dangerous goods. Avoid exposure to sunlight and heat during transit.
  • Bioavailability
  • Variable depending on route; subject to first-pass metabolism
  • IUPAC Name
  • (5,12)-19,20-dihydro-3-ethyl-5,12-epoxy-8,14,17,19-tetrahydroindolo[2,3-a]quinolizine-17-carboxylic acid methyl ester
  • Packing Type
  • HDPE bottles or glass vials, as per requirement
  • Stability
  • Stable under recommended storage conditions
  • Therapeutic Classification
  • Class I antiarrhythmic agent
  • Toxicity
  • May cause bradycardia, hypotension, or other adverse cardiac effects at overdose
  • Regulatory Status
  • Subject to pharmaceutical regulatory approvals
  • Quality Assurance
  • Complies with international pharmacopoeia standards
  • Hazard Statements
  • Use with caution. Toxic if ingested or in contact with skin in large doses.
  • Certificate of Analysis
  • Available upon request
 

Ajmaline Trade Information

  • Minimum Order Quantity
  • 50 Kilograms
  • Supply Ability
  • 1 Kilograms Per Week
  • Delivery Time
  • 1 Week
 

About Ajmaline

Ajmaline

Other Name    :  (17R,21)-ajmalan- 17,21-diol OR (1R,9R,10S,13R,14R,16S,18S)- 13-ethyl- 8-methyl- 8,15-diazahexacyclo [14.2.1.01,9.02,7.010,15.012,17] nonadeca- 2(7),3,5-triene- 14,18-diol

CAS Number     :  4360-12-7

Molecular Formula  :  C20H26N2O2

Application      : For use as an antiarrhythmic agent



High-Purity Pharmaceutical Grade Ajmaline

Ajmaline offered complies with international pharmacopoeia standards and is supplied as a white, crystalline powder intended for clinical, research, and pharmaceutical synthesis use. Packed in HDPE bottles or glass vials as per customer requirement, it is available from certified distributors, exporters, importers, manufacturers, and wholesalers in India. Each batch can be accompanied by a Certificate of Analysis upon request, assuring quality and traceability.


Storage and Handling Guidelines

Ajmaline should be stored in a cool, dry environment, away from light, to ensure its two-year shelf life and maintain stability. Since it is toxic in large doses, all handling must employ safety precautions to prevent ingestion, skin contact, and inhalation. During transport, Ajmaline is classified as dangerous goods and must be protected from direct sunlight and excess heat.

FAQs of Ajmaline:


Q: How is Ajmaline typically administered in clinical settings?

A: Ajmaline is usually administered either intravenously (IV) or orally, depending on the intended clinical application. The IV route is preferred for rapid action, especially in diagnosing or treating certain cardiac arrhythmias.

Q: What are the primary uses and benefits of Ajmaline?

A: Ajmaline is mainly used to diagnose and manage cardiac arrhythmias by stabilizing abnormal heart rhythms. Its rapid effect during IV administration is especially valuable for clinical diagnosis, including the confirmation of Brugada syndrome.

Q: When should Ajmaline be handled as a hazardous substance?

A: Ajmaline is considered hazardous and should be handled with caution at all times. It is toxic in large doses, may cause serious cardiac adverse effects, and requires appropriate protective measures during handling, transport, and storage.

Q: Where should Ajmaline be stored for optimal stability?

A: Store Ajmaline in a cool, dry place, protected from light, using its original container (HDPE bottle or glass vial). These conditions will help ensure its stability and full shelf life of up to two years.

Q: What is the process for obtaining a Certificate of Analysis for Ajmaline?

A: A Certificate of Analysis (CoA) can be provided upon request by the distributor or supplier. The CoA confirms the batch-specific quality, purity (98%), and compliance with international standards.

Q: How does the extraction source of Ajmaline affect its use?

A: Ajmaline can be extracted naturally from Rauwolfia serpentina or produced synthetically. Regardless of the source, it is subject to the same pharmaceutical standards for purity and efficacy.

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