About Pivaloyl chloride
Pivaloyl chloride
Cas No 3282302
Molecular Formula C5H9ClO
Appearance Colorless fuming liquid
Molecular Weight 120.58
Mp 56C
Bp 105106C
Density 0.980g
Fp 48F
Water Solubility Hydrolysis
Applications in Industrial SynthesisPivaloyl chloride finds primary use in pharmaceutical intermediates, agrochemical production, and organic synthesis. Its reactive acyl chloride group makes it effective for introducing pivaloyl moieties into target compounds. This broad applicability streamlines complex syntheses, supporting large-scale manufacturing and research.
Safety and Handling RecommendationsDue to its corrosive nature and Class 8 hazard classification, pivaloyl chloride should be handled only with suitable protective equipment in well-ventilated areas. Always avoid moisture contact, as it reacts vigorously with water, releasing corrosive gases. Storage in sealed HDPE containers, drums, or carboys, away from heat and humidity, is mandatory for user and environmental safety.
FAQs of Pivaloyl chloride:
Q: How should pivaloyl chloride be stored for maximum stability?
A: Pivaloyl chloride must be kept in tightly sealed containers, such as HDPE carboys or drums, stored in a cool, dry place, away from moisture and direct sunlight to maintain stability throughout its 24-month shelf life.
Q: What are the main benefits of using pivaloyl chloride in synthesis?
A: The primary benefit of pivaloyl chloride lies in its efficiency and high purity (99%), making it ideal for producing pharmaceutical intermediates, agrochemicals, and for use in organic synthesis, offering consistent results and ease of incorporation.
Q: When is specialized packaging required for pivaloyl chloride transport?
A: Specialized packaging is always required, using properly labeled HDPE containers or drums, because it is classified as a hazardous material (Class 8, UN 2511). Proper packaging ensures safety during transport and compliance with regulatory standards.
Q: What precautions are necessary during the use and handling of pivaloyl chloride?
A: Operators should wear protective clothing, gloves, and eye protection when handling pivaloyl chloride, avoid contact with water, and ensure all work is done in a well-ventilated area or fume hood to prevent inhalation of any harmful vapors.
Q: Where can pivaloyl chloride be sourced in India?
A: Pivaloyl chloride is available across India through various distributors, exporters, importers, manufacturers, retailers, suppliers, traders, and wholesalers. Custom packaging options such as 10 kg, 25 kg, and 200 kg drums cater to varied industrial requirements.
Q: What makes pivaloyl chloride a hazardous substance for aquatic environments?
A: Pivaloyl chloride is harmful to aquatic life due to its corrosive properties. Care should be taken to prevent any spills or release into waterways during use, storage, and disposal.