About Sodium Glycolate
Sodium Glycolate
CAS Number : 2836-32-0
Molecular Formula : C2H3NaO3
Molecular Weight : 98.03
Appearance : White Crystal
Assay : 99% Min
Water : 0.5% Max
Chloride : 0.2% Max
Sulphate : 0.1% Max
Heavy Metal : 10 ppm Max
Fe : 10 ppm Max
Cu : 10 ppm Max
Application : Sodium Glycolate is the salt of Glycolic Acid, and is used in cosmetics and personal care products primarily as an exfoliant or buffering agent, but also seen as pH adjusters and skin-conditioning agents.
High-Purity Pharmaceutical IngredientSodium Glycolate boasts an assay range of 98.0 102.0% and a purity of 99%, making it ideal for pharmaceutical applications. Thanks to its excellent disintegration properties, it enhances the efficacy of tablet formulations and meets global quality standards. The substance is odorless and appears as a white crystalline powder, signifying its superior grade and suitability for medical use.
Versatile Physical and Chemical PropertiesWith high solubility in water, a neutral pH (7.0 9.0 for a 2% solution), and exceptional stability, Sodium Glycolate ensures easy handling and compatibility with various formulations. Its melting point above 300C and low heavy metal content further emphasize safety and reliability, fulfilling pharmaceutical and industrial requirements.
Safe Storage and PackagingTo maintain its integrity, Sodium Glycolate should be stored in a cool, dry place and kept in an HDPE bag with a liner. This prevents contamination and retains its crystalline structure. The typical shelf life is two years, ensuring product stability and prolonged usability across different supply chains.
FAQs of Sodium Glycolate:
Q: How is Sodium Glycolate commonly used in pharmaceutical applications?
A: Sodium Glycolate is primarily utilized as a disintegrant in tablet formulations. It helps tablets break down efficiently after ingestion, ensuring rapid drug release and better absorption in the body.
Q: What process ensures the purity and quality of Sodium Glycolate?
A: The substance undergoes rigid quality controls, ensuring the assay remains between 98.0 102.0%. Additionally, checks for maximum loss on drying (5%), heavy metals (20 ppm), and iron content (10 ppm) guarantee pharmaceutical-grade quality.
Q: Where should Sodium Glycolate be stored for optimal stability?
A: To preserve its physical and chemical properties, Sodium Glycolate should be stored in a cool, dry environment, in an HDPE bag with a secure liner to avoid moisture or contamination.
Q: When should Sodium Glycolate be used in formulations?
A: It should be incorporated during the blending step of tablet manufacturing when a rapid disintegration profile is needed, particularly for immediate-release dosage forms.
Q: What are the main benefits of using Sodium Glycolate in industry?
A: Sodium Glycolate enhances the disintegration and dissolution of tablets, leading to improved drug bioavailability. Its stability and safety profile make it a preferred choice in high-quality pharmaceutical and industrial products.
Q: How does Sodium Glycolates solubility affect its application?
A: Being freely soluble in water and slightly soluble in alcohol, Sodium Glycolate disperses uniformly within tablet matrices, promoting consistent disintegration and absorption.
Q: What are the storage and packaging recommendations for Sodium Glycolate?
A: The product should be kept in tightly closed HDPE bags with liners, stored in cool, dry places to maintain its quality and extend its two-year shelf life.