About Ethyl Magnesium bromide
Ethyl Magnesium bromide
CAS number : 925-90-6
Molecular formula : C2H5BrMg
Mol. Wt.: 133.27
Mp : -116.3C
Bp : 34.6C
Density : 1.02 g/mL at 25C
Fp : <30F
Appearance : dark brown solution
Exceptional Reactivity for Advanced SynthesisEthyl Magnesium Bromide stands out as a cornerstone in organic synthesis, particularly in the formation of carbon-carbon bonds. Its use in Grignard reactions enables the creation of complex molecules, essential for developing pharmaceuticals and fine chemicals. With high purity (>97%) and analytical or technical grade options, it caters to professional needs by ensuring consistent, reliable performance in research and manufacturing environments.
Stringent Handling and Storage ProtocolsThis reagents high sensitivity to air and moisture demands careful storage and handling. It must be kept in tightly sealed glass bottles or ampoules under an inert atmosphere, such as argon or nitrogen. Proper precautions, including the use of appropriate gloves and protective equipment, are crucial to prevent hazardous reactions and ensure longevity, maintaining its reactive integrity throughout its 12-month shelf life.
FAQs of Ethyl Magnesium bromide:
Q: How should Ethyl Magnesium Bromide be stored to maintain its stability?
A: Ethyl Magnesium Bromide requires storage in glass bottles or ampoules under an inert atmosphere (such as argon or nitrogen) to prevent decomposition. Keep containers tightly closed and away from moisture and air, in a cool, well-ventilated area to ensure its stability for up to 12 months.
Q: What are the main uses of Ethyl Magnesium Bromide in chemical synthesis?
A: This reagent is primarily utilized in Grignard reactions for the alkylation process and formation of carbon-carbon bonds. Such reactions are fundamental in creating a variety of pharmaceuticals and specialty chemicals, making it indispensable for organic chemistry applications.
Q: When handling Ethyl Magnesium Bromide, what safety measures should be implemented?
A: Handle this chemical with extreme caution due to its corrosive and toxic nature. Protective gloves, goggles, and lab coats must be worn. Work in a well-ventilated fume hood, and avoid skin contact or inhalation, as it is poisonous. Always keep it away from water to prevent hazardous decomposition.
Q: Where is Ethyl Magnesium Bromide commonly applied or used?
A: It is widely used in academic and industrial laboratories, especially in organic synthetic procedures. Its primary applications include pharmaceutical manufacturing, chemical research, and the production of intermediates for more complex organic molecules.
Q: What benefit does Ethyl Magnesium Bromide offer over other organometallic reagents?
A: Its high reactivity and consistent purity make it ideal for reliable Grignard synthesis, facilitating efficient carbon-carbon bond formation. This translates to increased yield and efficiency in producing target molecules in organic pharmaceutical processes.
Q: How is Ethyl Magnesium Bromide typically supplied to customers?
A: It is usually provided as a 1.0 M solution in diethyl ether (or tetrahydrofuran), packaged in sealed glass bottles or ampoules under an inert gas to preserve quality and prevent reaction with atmospheric moisture.