About P-toluene Sulphonyl chloride
P-toluene Sulphonyl chloride
CAS No. : 98-59-9
Other Names : PTSC
Molecular Formula : C7H7CLO2S
Grade Standard : Industrial Grade, Reagent Grade, Analytics reagents.
Purity : 99% min
Appearance : White crystal
Application : Analytics reagents, also used in organic synthesis
Assay : 99% min.
Water : 0.5% Max.
Malting Point : 67 *C Min.
Tone : 30 max
Free acid : 0.1% max
Juxtaposition : 0.1% max
Boiling point: 265.3 C at 760 mmHg
Flash point : 114.3 C
Density : 1.339 g/cm3
Packaging Details : 25kg/fiber can. Key Properties and HandlingP-toluene Sulphonyl chloride presents as a crystalline solid with a distinct, pungent odor. Neutral in pH and highly pure, it is solvent in acetone and chloroform but unstable in water. Due to its toxic, irritant nature, proper safety measuresincluding gloves and eye protectionare essential during handling and storage. The product should be kept away from moisture and stored in tightly sealed containers to maintain stability.
Applications Across IndustriesExtensively used as a reagent and intermediate, P-toluene Sulphonyl chloride is crucial in the synthesis of pharmaceuticals, dyes, agrochemicals, and specialty compounds. Its primary application involves the tosylation process, where it modifies alcohols and amines to optimize downstream chemical reactions. The compound is distributed, exported, and supplied by a broad network in India catering to both domestic and international markets.
FAQs of P-toluene Sulphonyl chloride:
Q: How should P-toluene Sulphonyl chloride be safely stored and handled?
A: This compound should be stored in a tightly closed container, away from moisture and incompatible substances. Because it is poisonous and may cause irritation, always use suitable protective equipment such as gloves, goggles, and a lab coat when handling. Work in a well-ventilated area or under a fume hood to avoid inhalation of fumes.
Q: What is the primary industrial usage of P-toluene Sulphonyl chloride?
A: P-toluene Sulphonyl chloride is mainly used as a reagent in the tosylation of alcohols and amines, which transforms these functional groups into better leaving groups, facilitating further chemical synthesis. This reaction is crucial in the preparation of pharmaceuticals, dyes, agrochemicals, and specialty chemicals.
Q: When is P-toluene Sulphonyl chloride typically used in chemical synthesis?
A: It is commonly employed during the intermediate stages of organic synthesis, particularly when modifying alcohols or amines to allow for selective reactions or to enhance product yield and quality in the subsequent steps.
Q: Where can P-toluene Sulphonyl chloride be sourced in India?
A: This chemical is available through a variety of distributors, exporters, importers, manufacturers, retailers, suppliers, traders, and wholesalers across India. It is important to choose a reputable supplier to ensure product quality and compliance with safety regulations.
Q: What are the benefits of using P-toluene Sulphonyl chloride in synthesis?
A: Using P-toluene Sulphonyl chloride enables efficient transformation of functional groups, increasing reaction selectivity and yield. This enhances the production process in pharmaceuticals, dyes, and specialty chemicals, contributing to higher purity of end products.
Q: Is water a suitable solvent for P-toluene Sulphonyl chloride in laboratory processes?
A: No, water is not suitable since P-toluene Sulphonyl chloride decomposes upon contact with water. Instead, solvents like acetone and chloroform are preferred for dissolving and reacting this compound.