About Diethyl Sulphate (DES)
Diethyl Sulphate (DES)
Cas No.: 64-67-5
Molecular Formula : (C2H5)2SO4
Molecular Weight : 154.18
Appearance : A clear colorless, odourless liquid
Assay : 99.8% (min).
Acidity : 0.03 % (max)
Boiling Point : 208 °C with decomposition
Solubility : Soluble in Alcohol and Ether
Freezing Point : -24.5 C
Flash Point : 121 C Key Physical and Chemical PropertiesDiethyl Sulphate boasts a boiling point of 208C, a flash point of 113C (closed cup), and a density of 1.164 g/cm3. It is not self-igniting and has a molecular formula of C4H10O4S, with a refractive rate of 1.3931.396. Although soluble in alcohol and ether, it decomposes upon contact with water. Its colorless, clear nature and slightly ether-like smell distinguish it in industrial settings.
Safety and Handling PrecautionsThe hazardous nature of Diethyl Sulphate necessitates strict safety measures. Poisonous and carcinogenic, exposure can cause severe health effects by ingestion, inhalation, or skin contact. It should be stored tightly sealed in a cool, dry place away from heat and moisture. Hydrolysis occurs in moist air, further underscoring the need for diligent storage. Always use proper protective equipment and facilities for handling.
Industrial Applications and BenefitsDiethyl Sulphate is valued for its strong ethylating properties in organic synthesis and is extensively used as an intermediate in the preparation of dyes, pharmaceuticals, and agrochemicals. Its high reactivity enables targeted chemical transformations, improving efficiency and product yield in industrial manufacturing processes. Its stable nature when properly stored makes it reliable for various large-scale applications.
FAQs of Diethyl Sulphate (DES):
Q: How should Diethyl Sulphate be handled and stored to ensure safety?
A: Diethyl Sulphate should be tightly sealed in a cool, dry place, away from heat and moisture. Due to its toxicity and ability to hydrolyze in moist air, storage areas must be adequately ventilated, and handlers should use personal protective equipment to avoid skin contact or inhalation.
Q: What are the primary uses of Diethyl Sulphate in industry?
A: It is predominantly used as an ethylating agent in organic synthesis, serving as an intermediate for the manufacturing of dyes, pharmaceuticals, and agrochemicals. Its high reactivity ensures efficient industrial chemical transformations.
Q: When does Diethyl Sulphate become hazardous during transportation?
A: Diethyl Sulphate is classified under UN 1594 and Transport Hazard Class 6.1 (Toxic substance). It poses significant health risks if spilled, inhaled, or absorbed through the skin during transit, requiring specialized containers and strict regulations for shipment.
Q: Where is Diethyl Sulphate typically distributed and how is it packed?
A: Diethyl Sulphate is distributed globally by manufacturers, exporters, and traders. In India, it is supplied in 250 kg drums which are designed for safe transport and handling, reducing the chance of accidental exposure.
Q: What processes require Diethyl Sulphate as an intermediate or reagent?
A: DES is utilized in processes that involve organic synthesis, ethylation reactions, and the creation of key intermediates for dyes, pharmaceutical ingredients, and agrochemicals, due to its strong alkylating potential.
Q: What benefits does Diethyl Sulphate offer manufacturers in chemical synthesis?
A: Its high purity, reactive ethylating property, and stable nature make Diethyl Sulphate a preferred choice for enhancing yield and efficiency in large-scale chemical production, especially for high-value industrial products.