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5'-ODMT dT (PNS)

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5'-ODMT dT (PNS) Specification

Melting Point
168-172°C

Density
Gram per cubic centimeter(g/cm3)

Usage
Used as a protected nucleoside in the synthesis of DNA chains

Physical Form
Powder

Shelf Life
2 years from date of manufacturing

Poisonous
Non-poisonous under recommended handling

Product Type
Chemical Compound

Shape
Crystalline

Ph Level
Neutral (not in solution)

Taste
Odorless and tasteless

Molecular Weight
518.56 g/mol

Application
Synthesis of oligonucleotides, DNA research

Ingredients
5-O-(4,4-Dimethoxytrityl)thymidine

Grade
Molecular Biology Grade

Appearance
White to off-white powder

Properties
High purity, suitable for oligonucleotide synthesis

HS Code
29349900

Purity
>98% (HPLC)

Solubility
Soluble in acetonitrile, DMF, DMSO

CAS No
98796-53-3

Structural Formula
Available upon request

Storage
Store at -20°C, dry and dark conditions

Smell
Odorless

Molecular Formula
C29H30N2O7

Protecting Group
Dimethoxytrityl (DMT) group at 5' position

Hazard Information
Non-hazardous for transport

Stability
Stable under recommended storage and handling

Synonyms
5'-O-Dimethoxytritylthymidine; DMT-dT

Packaging Size
Available in 1g, 5g, 10g, and custom packaging

Purification
HPLC or silica gel chromatography

Regulatory Status
For research use only, not for human or animal therapeutic use

5'-ODMT dT (PNS) Trade Information

Supply Ability
100 Per Week

Delivery Time
1 Week

Main Export Market(s)
Western Europe, Australia, Eastern Europe, Middle East, Central America, South America, Asia, North America, Africa

Main Domestic Market
All India

About 5'-ODMT dT (PNS)

5'-ODMT dT (PNS)

CAS No : [40615-39-2]

M.Wt. 544.6

M.F.C31H32N2O7

Specification :

*Appearance: White to Off White Powder

*Purity by HPLC (%Area): NLT 98.0%

*1H NMR (Solvent:DMSO d6): Conforms with structure

*LCMS: Corresponds to Mass

*Moisture Content (KF w/w): NMT 1.0%

*Residual Solvents (%w/w): NMT 3.0%

*APHA in 0.2M DMSO solution: NMT 300

*Solubility: 0.2M in DMF

Premium Quality for DNA Synthesis

5-ODMT dT (PNS) delivers exceptional purity-above 98% by HPLC analysis-making it ideal for synthesizing oligonucleotides. Its crystalline, white to off-white powder form ensures consistency and ease of handling in both manual and automated synthesis processes. Carefully manufactured under stringent molecular biology standards, it helps researchers achieve reliable and reproducible results in demanding DNA and gene research projects.

Stable and Easy to Use

With a robust Dimethoxytrityl (DMT) protecting group at the 5 position, this product ensures efficient coupling and protection during oligonucleotide assembly. It is chemically stable under proper storage-dry, dark, and -20C-remaining effective for up to two years. The product dissolves readily in solvents like acetonitrile, DMF, or DMSO, accommodating a broad range of synthesis protocols.

Safe Handling and Versatile Sizing

Non-poisonous and non-hazardous for transport, 5-ODMT dT (PNS) aligns with the needs of safe laboratory practice. It is available in a variety of packaging sizes, including 1g, 5g, 10g, and custom options. Flexible quantities cater to diverse scales of DNA synthesis, from exploratory research to large production batches across India and global markets.

FAQ's of 5'-ODMT dT (PNS):

Q: How is 5-ODMT dT (PNS) typically used in the laboratory?

A: 5-ODMT dT (PNS) serves as a protected nucleoside in the chemical synthesis of DNA chains, playing a crucial role in automated oligonucleotide assembly for research and diagnostic applications.

Q: What benefits does the DMT protecting group provide during synthesis?

A: The Dimethoxytrityl (DMT) group at the 5-position protects the nucleoside during oligonucleotide synthesis, allowing for controlled, stepwise addition of nucleotides and easy removal under mild conditions.

Q: When should I consider using HPLC or silica gel chromatography for purification?

A: HPLC or silica gel chromatography should be used to ensure maximum purity, especially when preparing oligonucleotides for sensitive downstream applications such as genetic analysis or molecular diagnostics.

Q: Where should I store 5-ODMT dT (PNS) to ensure optimal stability?

A: Store the product at -20C in a dry, dark environment to maintain its quality and stability throughout its two-year shelf life.

Q: What safety precautions are necessary when handling 5-ODMT dT (PNS)?

A: 5-ODMT dT (PNS) is non-poisonous and non-hazardous during normal use. Standard laboratory safety protocols, including the use of gloves and eye protection, are recommended while handling the powder.