About Dimethyl Sulphate (DMS)
Dimethyl Sulphate (DMS)
Molecular Formula : C2H6O4S
Molecular Weight : 126.3
Description : A clear colorless, odourless liquid
Assay : 99.7% (min).
Specific Gravity : 1.323 to 1.330 at 20o/20oC
Acidity : 0.1% (max).
Boiling Point : 188 C with decomposition
Flash Point : 121 C (open cup)
Applications in Chemical IndustryDimethyl Sulphate serves as a key methylating agent for the synthesis of phenols, amines, and thiols. Its exceptional purity and reactive nature make it invaluable in producing pharmaceuticals, dyes, and agrochemicals. It is also used in research and development sectors for various organic transformations. Proper handling and adherence to safety regulations are essential due to its hazardous properties.
Storage and Handling PrecautionsDMS should be stored in a cool, dry, well-ventilated area in tightly sealed HDPE drums or steel containers. Adequate ventilation and protective gear are mandatory during handling to avoid inhalation or skin contact. It is critical to prevent interaction with strong bases and water, as these may trigger hazardous decomposition. Routine safety training is highly recommended for staff.
FAQs of Dimethyl Sulphate (DMS):
Q: How should Dimethyl Sulphate (DMS) be stored safely?
A: DMS must be stored in a cool, dry, well-ventilated area, tightly closed in HDPE drums or steel containers. Keep it away from strong bases and water to prevent dangerous reactions. Proper storage ensures stability and maintains shelf life for up to 12 months.
Q: What are the main applications of Dimethyl Sulphate?
A: DMS is primarily used as a methylating agent in organic synthesis, particularly for methylating phenols, amines, and thiols. It is important in producing pharmaceuticals, dyes, pesticides, and is also utilized in chemical research laboratories.
Q: When should special precautions be taken while using DMS?
A: Extra precautions are necessary at all times during handling, but particularly when transferring, measuring, or mixing, as DMS is highly toxic and flammable. Use adequate ventilation and wear protective equipment to prevent inhalation or skin contact.
Q: Where is Dimethyl Sulphate typically used or distributed in India?
A: DMS is supplied by authorized distributors, exporters, manufacturers, retailers, and wholesalers throughout India. It is found mainly in chemical industries, pharmaceutical plants, dye manufacturing units, and research laboratories requiring methylating agents.
Q: What is the process of using DMS in methylation reactions?
A: In methylation, DMS reacts with compounds such as phenols, amines, or thiols under controlled conditions. The process is performed in specialized facilities using strict safety measures due to its toxicity and potential for decomposition into methanol and sulfur oxides.
Q: What benefits does DMS provide in industrial applications?
A: DMS offers reliable methylation, high reaction efficiency, and industrial-grade purity. Its controlled use enables efficient synthesis of complex organic compounds within pharmaceuticals, dyes, and pesticides, making it a valuable reagent for multiple sectors.