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5 -O-(4,4-dimethoxytrityl)-deoxythymidine

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5 -O-(4,4-dimethoxytrityl)-deoxythymidine

Name: 5 -O-(4,4-dimethoxytrityl)-deoxythymidine
Brand: A. B. ENTERPRISES
Price: 8200 INR
Availability: InStock

Price 8200 INR/ Kilograms

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MOQ : 25 Grams

5 -O-(4,4-dimethoxytrityl)-deoxythymidine Specification

Structural Formula
See image or refer to structural diagram in documentation

Appearance
White to off-white crystalline powder

Molecular Weight
518.56 g/mol

Usage
Used as a protected deoxythymidine in automated DNA synthesis

Refractive Rate
Not determined

CAS No
98796-53-3

Ingredients
5-O-(4,4-dimethoxytrityl)-2-deoxythymidine

Product Type
Nucleoside derivative

Taste
Not determined

Purity
98%

Poisonous
Non-poisonous

Shape
Crystalline

Properties
Protecting group on deoxythymidine for use in oligonucleotide synthesis; sensitive to acid for removal; DMT-protected nucleoside

Application
Oligonucleotide synthesis, DNA research, molecular biology

Grade
Research grade

Solubility
DMSO, DMF, dichloromethane, methanol

Physical Form
Solid

HS Code
29349990

Melting Point
185-190C

Storage
Store at -20C, dry and protected from light

Density
Gram per cubic centimeter(g/cm3)

Molecular Formula
C29H30N2O7

Smell
Odorless

Shelf Life
2 years under recommended storage

Synonyms
DMT-dT

Handling Precautions
Use gloves and eye protection; avoid inhalation

Packaging Type
Sealed container, light-protected

Standard
Meets analytical standards for oligonucleotide synthesis

Protecting Group
Dimethoxytrityl (DMT) at 5'-hydroxyl position

End Use
Chemical intermediates; research reagents

Transport Condition
Ambient temperature; avoid direct sunlight

Stability
Stable under recommended storage conditions

5 -O-(4,4-dimethoxytrityl)-deoxythymidine Trade Information

Minimum Order Quantity
25 Grams

Supply Ability
100 Grams Per Week

Delivery Time
1 Week

Main Export Market(s)
South America, Asia, Eastern Europe, Central America, Middle East, Western Europe, North America, Australia, Africa

Main Domestic Market
All India

About 5 -O-(4,4-dimethoxytrityl)-deoxythymidine

5'-O-(4,4-dimethoxytrityl)-deoxythymidine,

CAS No : [40615-39-2]

M.Wt. 544.6

M.F.C31H32N2O7

Specification :

*Appearance: White to Off White Powder

*Purity by HPLC (%Area): NLT 98.0%

*1H NMR (Solvent:DMSO d6): Conforms with structure

*LCMS: Corresponds to Mass

*Moisture Content (KF w/w): NMT 1.0%

*Residual Solvents (%w/w): NMT 3.0%

*APHA in 0.2M DMSO solution: NMT 300

*Solubility: 0.2M in DMF

Reliable Protection for DNA Synthesis

DMT-dT is essential in oligonucleotide synthesis, offering reliable protection for the 5 hydroxyl group of deoxythymidine. Its DMT group is easily removable under acidic conditions, facilitating efficient and precise synthesis cycles in both automated and manual processes. The compounds high purity and stability make it a trusted component for researchers focusing on DNA assembly and sequencing methodologies in molecular biology.

Safe Handling and Versatile Applications

Supplied as a stable, odorless, and non-poisonous crystalline powder, DMT-dT requires basic laboratory precautions such as gloves and eye protection during use. Its versatility as an intermediate in DNA research and a reagent in oligonucleotide assembly highlights its importance for laboratories engaged in genetic analysis, diagnostics, and synthetic biology.

FAQs of 5 -O-(4,4-dimethoxytrityl)-deoxythymidine:

Q: How should 5-O-(4,4-dimethoxytrityl)-deoxythymidine be stored for maximum stability?

A: Store DMT-dT at -20C in a dry, light-protected environment to maintain its stability and preserve its shelf life for up to two years.

Q: What is the main use of DMT-dT in molecular biology?

A: DMT-dT serves as a protected nucleoside for the synthesis of oligonucleotides, acting as a key intermediate in DNA assembly and automated DNA synthesizers.

Q: When should the DMT protecting group be removed during oligonucleotide synthesis?

A: The DMT group is removed under acidic conditions at specific steps in the synthesis process to expose the 5-hydroxyl group, enabling continued chain elongation.

Q: Where can DMT-dT be purchased, and in what forms is it available?

A: DMT-dT is supplied by distributors, exporters, importers, manufacturers, retailers, suppliers, traders, and wholesalers in India, typically in sealed, light-protected containers as a white to off-white crystalline solid.

Q: What are the handling precautions for DMT-dT in the laboratory?

A: Wear gloves and eye protection when working with DMT-dT, and ensure the laboratory is well ventilated to avoid inhalation of dust, even though the compound is non-poisonous and odorless.

Q: How does the DMT protecting group benefit the DNA synthesis process?

A: The DMT group ensures selectivity and efficiency during oligonucleotide synthesis by protecting the 5-hydroxyl position and allowing controlled deprotection at the correct synthesis stage.