5 -O-(4,4-dimethoxytrityl)-deoxythymidine

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5 -O-(4,4-dimethoxytrityl)-deoxythymidine

Price 8200 INR/ Kilograms

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MOQ : 25 Grams

5 -O-(4,4-dimethoxytrityl)-deoxythymidine Specification

Shelf Life
2 years under recommended storage

Properties
Protecting group on deoxythymidine for use in oligonucleotide synthesis; sensitive to acid for removal; DMT-protected nucleoside

Physical Form
Solid

Appearance
White to off-white crystalline powder

Smell
Odorless

Usage
Used as a protected deoxythymidine in automated DNA synthesis

Poisonous
Non-poisonous

CAS No
98796-53-3

Structural Formula
See image or refer to structural diagram in documentation

Purity
98%

Solubility
DMSO, DMF, dichloromethane, methanol

Taste
Not determined

Molecular Formula
C29H30N2O7

Refractive Rate
Not determined

Density
Gram per cubic centimeter(g/cm3)

Product Type
Nucleoside derivative

Shape
Crystalline

Grade
Research grade

Melting Point
185-190C

HS Code
29349990

Ingredients
5-O-(4,4-dimethoxytrityl)-2-deoxythymidine

Application
Oligonucleotide synthesis, DNA research, molecular biology

Molecular Weight
518.56 g/mol

Storage
Store at -20C, dry and protected from light

5 -O-(4,4-dimethoxytrityl)-deoxythymidine Trade Information

Minimum Order Quantity
25 Grams

Supply Ability
100 Grams Per Week

Delivery Time
1 Week

Main Export Market(s)
South America, Asia, Eastern Europe, Central America, Middle East, Western Europe, North America, Australia, Africa

Main Domestic Market
All India

About 5 -O-(4,4-dimethoxytrityl)-deoxythymidine

5'-O-(4,4-dimethoxytrityl)-deoxythymidine,

CAS No : [40615-39-2]

M.Wt. 544.6

M.F.C31H32N2O7

Specification :

*Appearance: White to Off White Powder

*Purity by HPLC (%Area): NLT 98.0%

*1H NMR (Solvent:DMSO d6): Conforms with structure

*LCMS: Corresponds to Mass

*Moisture Content (KF w/w): NMT 1.0%

*Residual Solvents (%w/w): NMT 3.0%

*APHA in 0.2M DMSO solution: NMT 300

*Solubility: 0.2M in DMF

Reliable Protection for DNA Synthesis

DMT-dT is essential in oligonucleotide synthesis, offering reliable protection for the 5 hydroxyl group of deoxythymidine. Its DMT group is easily removable under acidic conditions, facilitating efficient and precise synthesis cycles in both automated and manual processes. The compounds high purity and stability make it a trusted component for researchers focusing on DNA assembly and sequencing methodologies in molecular biology.

Safe Handling and Versatile Applications

Supplied as a stable, odorless, and non-poisonous crystalline powder, DMT-dT requires basic laboratory precautions such as gloves and eye protection during use. Its versatility as an intermediate in DNA research and a reagent in oligonucleotide assembly highlights its importance for laboratories engaged in genetic analysis, diagnostics, and synthetic biology.

FAQs of 5 -O-(4,4-dimethoxytrityl)-deoxythymidine:

Q: How should 5-O-(4,4-dimethoxytrityl)-deoxythymidine be stored for maximum stability?

A: Store DMT-dT at -20C in a dry, light-protected environment to maintain its stability and preserve its shelf life for up to two years.

Q: What is the main use of DMT-dT in molecular biology?

A: DMT-dT serves as a protected nucleoside for the synthesis of oligonucleotides, acting as a key intermediate in DNA assembly and automated DNA synthesizers.

Q: When should the DMT protecting group be removed during oligonucleotide synthesis?

A: The DMT group is removed under acidic conditions at specific steps in the synthesis process to expose the 5-hydroxyl group, enabling continued chain elongation.

Q: Where can DMT-dT be purchased, and in what forms is it available?

A: DMT-dT is supplied by distributors, exporters, importers, manufacturers, retailers, suppliers, traders, and wholesalers in India, typically in sealed, light-protected containers as a white to off-white crystalline solid.

Q: What are the handling precautions for DMT-dT in the laboratory?

A: Wear gloves and eye protection when working with DMT-dT, and ensure the laboratory is well ventilated to avoid inhalation of dust, even though the compound is non-poisonous and odorless.

Q: How does the DMT protecting group benefit the DNA synthesis process?

A: The DMT group ensures selectivity and efficiency during oligonucleotide synthesis by protecting the 5-hydroxyl position and allowing controlled deprotection at the correct synthesis stage.