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Sodium bis(trimethylsilyl)amide(1M & 2M soln.)

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Sodium bis(trimethylsilyl)amide(1M & 2M soln.)

Name: Sodium bis(trimethylsilyl)amide(1M & 2M soln.)
Brand: A. B. ENTERPRISES

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MOQ : 50 Kilograms

Sodium bis(trimethylsilyl)amide(1M & 2M soln.) Specification

Molecular Weight
181.38 g/mol

CAS No
1070-89-9

Other Names
Sodium hexamethyldisilazide; NaHMDS

Solubility
Soluble in THF, hydrocarbons

Boiling point
Depending on solvent, approx. 65-80°C

Poisonous
Yes, harmful if swallowed or inhaled

Physical Form
Liquid

Molecular Formula
C6H18NNaSi2

Purity
1M & 2M in THF or Hexane

Grade
Analytical / Laboratory

Structural Formula
((CH3)3Si)2NNa

Appearance
Colourless to pale yellow solution

Density
0.88 Gram per cubic centimeter(g/cm3)

EINECS No
213-999-5

Shape
Liquid (solution)

Melting Point
< -20°C (for the solution)

Smell
Ammoniacal

HS Code
29209095

Ph Level
Strongly basic

Storage Condition
Store under inert atmosphere (argon or nitrogen), keep tightly closed, protect from moisture

Water Reactivity
Reacts violently with water

Hazard Class
Dangerous, flammable liquids (depending on solvent)

Decomposition
Decomposes in presence of moisture to produce hexamethyldisilazane and NaOH

Sensitivity
Air and moisture sensitive

Packaging
Supplied in sealed bottles or ampules under inert atmosphere

Uses
Strong, non-nucleophilic base for organic synthesis, especially in deprotonation and enolate chemistry

Sodium bis(trimethylsilyl)amide(1M & 2M soln.) Trade Information

Minimum Order Quantity
50 Kilograms

Supply Ability
1 Kilograms Per Week

Delivery Time
1 Week

About Sodium bis(trimethylsilyl)amide(1M & 2M soln.)

Sodium bis(trimethylsilyl)amide(1M & 2M soln.)

CAS No : 1070-89-9

Formula: [(CH3)3Si]2NNa

Molecular Weight: 183.37

Appearance: Clear yellow to brown liquid

Assay : Depend upon mole solution

Powerful Non-Nucleophilic Base for Organic Synthesis

Sodium bis(trimethylsilyl)amide offers exceptional strength and selectivity in deprotonation reactions. Its non-nucleophilic characteristic makes it highly advantageous for creating enolates and carrying out transformations where minimal side reactions are crucial. Supplied in precise concentrations, it ensures reliability and reproducibility for laboratory and industrial applications.

Safe Handling and Storage Requirements

Due to its high sensitivity to air and moisture, NaHMDS solutions must be stored tightly closed under an inert atmosphere such as argon or nitrogen. Direct exposure to moisture leads to rapid and violent reactions, emphasizing the importance of sealed packaging and safe laboratory practices. Always use appropriate protective equipment when handling this chemical.

FAQs of Sodium bis(trimethylsilyl)amide(1M & 2M soln.):

Q: How should Sodium bis(trimethylsilyl)amide solutions be stored safely?

A: Sodium bis(trimethylsilyl)amide solutions should be stored under an inert atmosphere, such as argon or nitrogen, in tightly closed containers. Keep them away from moisture and sources of ignition to maintain product integrity and prevent hazardous decomposition.

Q: What happens when NaHMDS solutions come into contact with water?

A: NaHMDS reacts violently with water, leading to rapid decomposition and the formation of hexamethyldisilazane and sodium hydroxide. This reaction is hazardous, so avoid moisture exposure during storage and use.

Q: When is it advantageous to use Sodium bis(trimethylsilyl)amide in organic synthesis?

A: NaHMDS is particularly valuable in deprotonation and enolate chemistry, especially when a strong, non-nucleophilic base is needed to avoid unwanted side reactions. Its use improves selectivity and efficiency in sensitive transformations.

Q: Where can NaHMDS (1M & 2M solution) be sourced in India?

A: NaHMDS can be obtained from authorized distributors, exporters, importers, manufacturers, retailers, suppliers, traders, and wholesalers across India, typically packaged in sealed bottles or ampules under inert atmosphere.

Q: What are the benefits of using NaHMDS compared to other bases?

A: NaHMDS combines strong basicity with non-nucleophilic properties, minimizing side reactions in complex syntheses. Its standardized solutions provide consistent results for demanding laboratory and industrial uses.

Q: What precautions should be taken during the handling process of NaHMDS solutions?

A: Always wear suitable protective equipment, such as gloves and eye protection, and work in well-ventilated areas. Handle only under inert atmosphere and ensure all equipment is dry, as the chemical is highly sensitive to air and moisture.

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