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5 -O-(4,4'-dimethoxytrityl)-N6-Benzoyl-2'-deoxyadenosine

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5 -O-(4,4'-dimethoxytrityl)-N6-Benzoyl-2'-deoxyadenosine

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5 -O-(4,4'-dimethoxytrityl)-N6-Benzoyl-2'-deoxyadenosine Specification

Melting Point
175-185C (decomposition)

Appearance
White to off-white powder

Molecular Formula
C40H37N5O7

Storage
Store at 20C, dry, protected from light

Purity
>98% (HPLC)

Density
Gram per cubic centimeter(g/cm3)

Poisonous
Non-poisonous

CAS No
95996-01-7

Application
Oligonucleotide synthesis, DNA research

Molecular Weight
699.76 g/mol

Physical Form
Solid

Properties
Protecting groups at 5 (DMT) and N6 (Bz), suitable for oligonucleotide synthesis

Structural Formula
See accompanying image or chemical structure (C40H37N5O7)

Grade
Research Grade

Shape
Crystalline powder

Ingredients
5-O-(4,4-dimethoxytrityl)-N6-benzoyl-2-deoxyadenosine

Product Type
Nucleoside Derivative

HS Code
29349990

Solubility
Soluble in DMF, DMSO, and methanol

Smell
Odorless

Taste
Not determined

Usage
Intermediate for automated DNA synthesis

Shelf Life
2 years under proper storage

Hazard Information
Non-hazardous for transportation

UN Number
Not regulated

Protecting Groups
5-DMT, N6-Benzoyl (Bz)

Packing Type
Sealed amber vial

Stability
Stable under recommended conditions

Synonyms
5'-O-(4,4'-Dimethoxytrityl)-N6-benzoyl-2'-deoxyadenosine, DMT-dA(Bz)

Chemical Family
Purine Nucleoside

5 -O-(4,4'-dimethoxytrityl)-N6-Benzoyl-2'-deoxyadenosine Trade Information

Supply Ability
100 Per Week

Delivery Time
1 Week

Main Export Market(s)
Australia, North America, Eastern Europe, Middle East, Central America, South America, Western Europe, Asia, Africa

Main Domestic Market
All India

About 5 -O-(4,4'-dimethoxytrityl)-N6-Benzoyl-2'-deoxyadenosine

5'-O-(4,4'-dimethoxytrityl)-N6-Benzoyl-2'-deoxyadenosine

CAS No : [64325-78-6]

M.Wt. 657.7

M.F. C38H35N5O6

Specification :

*Appearance: White to Off White Powder

*Purity by HPLC (%Area): NLT 98.0%

*1H NMR (Solvent:DMSO d6): Conforms with structure

*LCMS: Corresponds to Mass

*Moisture Content (KF w/w): NMT 1.0%

*Residual Solvents (%w/w): NMT 3.0%

*APHA in 0.2M DMSO solution: NMT 300

*Solubility: 0.2M in DMF

Superior Nucleoside Protection for DNA Synthesis

5-O-(4,4-dimethoxytrityl)-N6-Benzoyl-2-deoxyadenosine features both 5-DMT and N6-benzoyl protecting groups, crucial for high-yield and selective oligonucleotide assembly. With its high purity and strong stability, this compound supports reliable, efficient automated DNA synthesis, making it a staple in DNA research and development laboratories.

Easy Handling and Broad Solubility

This nucleoside is provided as a crystalline powder that readily dissolves in solvents such as DMF, DMSO, and methanol. Its odorless, non-toxic nature and non-hazardous classification streamline routine handling and transportation. Packaged in sealed amber vials, it is safeguarded against moisture and light for maximum efficacy.

FAQ's of 5 -O-(4,4'-dimethoxytrityl)-N6-Benzoyl-2'-deoxyadenosine:

Q: How is 5-O-(4,4-dimethoxytrityl)-N6-Benzoyl-2-deoxyadenosine used in oligonucleotide synthesis?

A: This compound acts as a key intermediate in automated DNA synthesis, providing both 5 DMT and N6 benzoyl protecting groups essential for stepwise nucleotide addition and ensuring sequence fidelity in the final oligonucleotide product.

Q: What are the recommended storage and handling conditions?

A: Store the compound at -20C, in a dry location, and protect it from light by keeping it in the sealed amber vial provided. Proper storage under these conditions maintains stability for up to two years.

Q: When should I choose this nucleoside for my research?

A: Opt for this protected deoxyadenosine analog when high purity and reliable protection are essential for sensitive oligonucleotide and DNA synthesis, especially in automated procedures requiring minimal side reactions.

Q: Where can this product be sourced and what forms is it available in?

A: 5-O-(4,4-dimethoxytrityl)-N6-Benzoyl-2-deoxyadenosine is available through distributors, exporters, importers, manufacturers, and retailers in India, supplied as a crystalline white to off-white powder in sealed amber vials.

Q: What are the primary benefits of using this protected nucleoside?

A: The compound ensures effective blocking of reactive sites, preventing undesired reactions during DNA chain elongation. Its high purity and stability result in improved yields and reproducibility in oligonucleotide synthesis.

Q: Is this compound hazardous or poisonous for handling and transport?

A: No, the compound is classified as non-poisonous and non-hazardous for transportation. Normal laboratory safety precautions suffice when handling this product.

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