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Glibenclamide

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MOQ : 10 Grams, Gram

Glibenclamide Specification

Poisonous
No (when used as directed)

Product Type
Active Pharmaceutical Ingredient

Usage
Oral antidiabetic agent

Shape
Crystalline

Appearance
White crystalline powder

Molecular Weight
494.01 g/mol

Grade
Pharmaceutical Grade

Solubility
Practically insoluble in water, soluble in dimethylformamide and slightly soluble in alcohol

Molecular Formula
C23H28ClN3O5S

Shelf Life
36 months

Ingredients
Glibenclamide (API)

Taste
Odourless or slightly bitter

Physical Form
Powder

Smell
Odourless

HS Code
29420090

Structural Formula
[Structural formula as per Glibenclamide chemical structure]

Purity
99%

Ph Level
Neutral

Density
1.23 Gram per cubic centimeter(g/cm3)

Refractive Rate
Not available

Application
Used in treatment of type 2 diabetes mellitus

Glibenclamide Trade Information

Minimum Order Quantity
10 Grams, Gram

Supply Ability
1 Gram Per Week

Delivery Time
1 Week

About Glibenclamide

Glibenclamide

Formula : C₂₃H₂₈ClN₃O₅S

CAS No. : 10238-21-8

Uses : Antidiabetic, Hypoglycemic Agent.

Impurity A : 5-chloro-2-methoxy-N-[2-(4-sulphamoylphenyl)ethyl]benzamide,	0.5%
Impurity B : methoxybenzoyl)amino]ethyl]phenyl]sulphonyl]carbamate.	0.5%
Unknown Impurity 1	0.2%
Unknown Impurity 2	0.1 %
Unknown Impurity 3	0.1%
Total of other impurities	0.5

Key Features of Glibenclamide

With its high purity level of 99% or more, Glibenclamide is a trusted choice for pharmaceutical applications requiring reliable results. Its stability throughout its 36-month shelf life ensures suitability for storage and distribution. Being practically insoluble in water gives it predictable pharmacokinetic characteristics, while solubility in certain organic solvents allows for flexible formulation routes.

Applications and Benefits

Glibenclamide is primarily used as an oral antidiabetic agent for the treatment of type 2 diabetes mellitus. Its efficacy in lowering blood sugar makes it valuable for patients requiring glucose regulation. The substances pharmaceutical grade ensures it meets rigorous safety and quality criteria, making it suitable for formulation into tablets or other oral medication forms. Safe usage, without poisonous effects when used as directed, offers further confidence for pharmacists and healthcare providers.

FAQs of Glibenclamide:

Q: How is Glibenclamide commonly used in the treatment of type 2 diabetes?

A: Glibenclamide is used orally as an antidiabetic agent to help control blood sugar levels in individuals diagnosed with type 2 diabetes mellitus. It works by stimulating insulin release from the pancreas, improving the bodys ability to regulate glucose.

Q: What are the physical and chemical forms in which Glibenclamide is available?

A: This product is provided as a white, crystalline powder that is odourless or only slightly bitter. Its chemical identity is Glibenclamide (C23H28ClN3O5S), containing a molecular weight of 494.01 g/mol, and it is classified as a pharmaceutical-grade substance with a high purity of at least 99%.

Q: When should Glibenclamide be considered for pharmaceutical formulation?

A: Glibenclamide is suitable for formulation when developing oral antidiabetic medications for patients with type 2 diabetes. Its long shelf life of 36 months and stable crystalline form make it a reliable choice for manufacturing and compounding.

Q: Where can Glibenclamide be sourced in India?

A: Glibenclamide is available throughout India via distributors, exporters, importers, manufacturers, suppliers, traders, retailers, and wholesalers, making it broadly accessible for various pharmaceutical and medical applications.

Q: What is the recommended process for handling and formulating Glibenclamide?

A: Glibenclamide should be handled in accordance with pharmaceutical manufacturing standards, including the use of appropriate PPE. It can be formulated into tablets or other oral dosage forms using solvents such as dimethylformamide or alcohol, given its specific solubility profile.

Q: What are the main benefits of using pharmaceutical-grade Glibenclamide?

A: Pharmaceutical-grade Glibenclamide provides high purity and stable activity, ensuring consistent therapeutic outcomes in type 2 diabetes management. It is odourless, generally considered non-poisonous when used correctly, and offers a predictable shelf life and handling profile.

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