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5'-ODMT-2-OTBDMS-N-Ac C,

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5'-ODMT-2-OTBDMS-N-Ac C, Specification

Poisonous
NO

CAS No
175595-63-8

Structural Formula
See image or refer to product literature

Appearance
White to off-white solid

Product Type
Nucleoside Derivative (Cytidine Analog)

Density
Gram per cubic centimeter(g/cm3)

Purity
>98% (HPLC)

Refractive Rate
Not determined

Storage
Store at -20C, in a dry, dark place

Usage
Laboratory chemical for nucleic acid synthesis

Shelf Life
12 months (when stored properly)

Solubility
Soluble in organic solvents such as acetonitrile and dichloromethane

Molecular Weight
799.98 g/mol

Application
Oligonucleotide synthesis; DNA/RNA modification

Taste
Not determined

Shape
Crystalline Powder

Molecular Formula
C43H53N3O9Si

Properties
Protecting group modified cytidine; hydrophobic base and 2-O protection

Physical Form
Powder

Smell
Odorless

Ingredients
5-O-Dimethoxytrityl-2-O-Tert-butyldimethylsilyl-N-Acetyl Cytidine

HS Code
29349900

Grade
Research / Laboratory grade

Synonyms
5-O-Dimethoxytrityl-2-O-tert-butyldimethylsilyl-N4-acetyl Cytidine; DMT-TBDMS-N-Ac Cytidine

Quality Control
Tested by HPLC, MS, and NMR

Transport Conditions
Ambient, avoid moisture exposure

Moisture Content
<1% by weight

Regulatory Status
For R&D use; not for drug, agricultural or food use

Safety Note
Handle with appropriate PPE; for laboratory use only

Stability
Stable under recommended storage

Packaging
Available in 100 mg, 500 mg, 1 g packs

Impurities
2% total impurities

5'-ODMT-2-OTBDMS-N-Ac C, Trade Information

Supply Ability
100 Per Week

Delivery Time
1 Week

Main Export Market(s)
Western Europe, Australia, North America, South America, Eastern Europe, Middle East, Central America, Asia, Africa

Main Domestic Market
All India

About 5'-ODMT-2-OTBDMS-N-Ac C,

5'-ODMT-2-OTBDMS-N-Ac C,

CAS No : [121058-85-3]

M.Wt. 701.88

M.F. C38H47N3O8Si

Specification :

*Appearance: White to Off white powder,

*HPLC Purity: NLT 98%

*5'-ODMT-2'-OTBDMS Uridine (3'-Isomer): NMT 0.3%

*Residual Solvent: NMT 3.0%

*Moisture content by KF: NMT 1.0%

*1H NMR (Solvent : DMSO d6): Conforms with Structure

*LCMS: Corresponds to Mass

*APHA Test in 0.2M in DMSO: NMT 250

*Solubility: 0.2M in MDC

Advanced Cytidine Protection

5-ODMT-2-OTBDMS-N-Ac C features dual protection through DMT and TBDMS groups, securing both the 5-hydroxyl and the 2-hydroxyl positions, and N4-acetylation. This makes it a valuable monomer in automated nucleic acid synthesis, offering researchers improved control during oligonucleotide assembly and reduced side-reactions.

High Purity and Reliable Quality

Manufactured for laboratory applications, this cytidine analogue exceeds 98% purity as verified by HPLC, MS, and NMR. Strict quality protocols and moisture content below 1% guarantee consistent results, supporting both routine and advanced experimental workflows in nucleic acid research.

Convenient Handling and Storage

The compound is supplied as a white to off-white odorless crystalline powder, with stability assured for at least 12 months when stored dry at -20C, away from light. Packaging options range from 100 mg to 1 g, catering to different research scales. Ambient shipping simplifies logistics, provided moisture is avoided.

FAQ's of 5'-ODMT-2a-OTBDMS-N-Ac C,:

Q: How should 5-ODMT-2-OTBDMS-N-Ac C be stored to ensure maximum stability?

A: For optimal stability, keep the product at -20C in a dry, dark environment, protected from moisture. This preserves its quality for up to 12 months.

Q: What are the main applications of this protected cytidine derivative in the laboratory?

A: It is primarily used in oligonucleotide synthesis and DNA/RNA modification, facilitating efficient and selective incorporation of cytidine into synthetic nucleic acids.

Q: When is it necessary to employ both DMT and TBDMS protecting groups in nucleotide synthesis?

A: Utilization of these groups is essential during solid-phase oligonucleotide synthesis, where selective protection of the 5 and 2-hydroxyl groups prevents undesired reactions and allows sequential assembly of nucleic acids.

Q: Where is this compound typically utilized in research settings?

A: This compound is commonly employed in biotechnology, molecular biology, and synthetic biology laboratories focused on nucleic acid research and development.

Q: What quality control measures are used to assess the product's purity and suitability for research?

A: Each batch is thoroughly tested by high-performance liquid chromatography (HPLC), mass spectrometry (MS), and nuclear magnetic resonance (NMR) to confirm >98% purity and structural integrity.

Q: How can researchers benefit from using this compound in their oligonucleotide syntheses?

A: By using this modified cytidine, researchers gain enhanced control over nucleotide incorporation, achieve higher fidelity during synthesis, and reduce unwanted side reactions due to the efficient protection of functional groups.

Q: What is the process for dissolving 5-ODMT-2-OTBDMS-N-Ac C for laboratory use?

A: The compound should be dissolved in organic solvents, such as acetonitrile or dichloromethane, ensuring a suitable medium for subsequent synthetic procedures.

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