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Methyl Magnesium Chloride 3 M in THF

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MOQ : 50 Kilograms

Methyl Magnesium Chloride 3 M in THF Specification

Product Type
Organometallic compound

CAS No
676-58-4

Solubility
Soluble in THF, reacts with water

Grade
Laboratory/Reagent Grade

Smell
Pungent, ether-like odor

Structural Formula
CH3MgCl

Usage
As a methylating agent in synthesis of alcohols, pharmaceuticals, fine chemicals

Molecular Formula
CH3MgCl

HS Code
28259090

Density
0.950 Gram per cubic centimeter(g/cm3)

Poisonous
Yes, toxic reagent

Shelf Life
12 months (if unopened and stored as recommended)

Purity
3 M solution in THF

Shape
Liquid

Refractive Rate
1.41 1.43 (approximate, solution)

Ingredients
Methyl Magnesium Chloride in Tetrahydrofuran (THF)

Physical Form
Liquid

Appearance
Colorless to pale yellow liquid

Properties
Highly reactive, moisture sensitive, flammable, organometallic Grignard reagent

Melting Point
Not applicable (solution)

Application
Used in organic synthesis, Grignard reactions, introduction of methyl group

EINECS No
211-622-9

Molecular Weight
74.78 g/mol

Ph Level
Highly basic (incompatible with aqueous media)

Storage
Store under inert atmosphere (argon/nitrogen), protect from air, moisture, and light at 2-8C

Methyl Magnesium Chloride 3 M in THF Trade Information

Minimum Order Quantity
50 Kilograms

Supply Ability
1 Kilograms Per Week

Delivery Time
1 Week

About Methyl Magnesium Chloride 3 M in THF

Methyl Magnesium Chloride 3 M in THF

FORMULA: CH3MgCI

MOL. Wt.: 74.49 gm/mole

CAS NO.: 676-58-4

Appearance: Grayish coloured viscous liquid

SOLUBILITY: Soluble in Alcohol & Water

DENSITY: 1.01 - 1.02

ASSAY: NLT 23.0% w/w.

Exceptional Reactivity for Synthetic Applications

Methyl Magnesium Chloride is prized for its vigorous reactivity, making it ideal for Grignard reactions in organic synthesis. It efficiently delivers methyl groups to target molecules, which is crucial in the production of alcohols, pharmaceuticals, and fine chemicals. Its high purity and stability when stored under recommended conditions ensure consistent performance in laboratory and industrial processes.

Safe Packaging and Storage

To preserve its integrity, Methyl Magnesium Chloride 3 M in THF is offered in sealed glass bottles or ampoules under an inert gas atmosphere. Proper storage at 28C in a dry, protected environment is essential for maintaining shelf life and preventing hazardous decomposition due to moisture or air exposure. This attention to packaging ensures product reliability and user safety.

FAQs of Methyl Magnesium Chloride 3 M in THF:

Q: How should Methyl Magnesium Chloride 3 M in THF be handled safely?

A: This reagent must be handled under strict dry, inert conditions using protective equipment such as gloves and eye protection, as it is highly moisture sensitive, flammable, and toxic. Avoid contact with air, water, and incompatible chemicals including acids and oxidizing agents to prevent hazardous reactions.

Q: What is the primary application of Methyl Magnesium Chloride 3 M in THF in organic synthesis?

A: It is mainly used as a methylating agent in Grignard reactions, facilitating the incorporation of methyl groups into organic molecules. This process is essential in synthesizing alcohols, pharmaceutical ingredients, and specialty fine chemicals.

Q: When is this reagent most beneficial in laboratory procedures?

A: Methyl Magnesium Chloride proves most beneficial during preparative organic synthesis where targeted methyl introduction is required, especially when working on projects that demand high reactivity and selectivity under controlled anhydrous conditions.

Q: Where should Methyl Magnesium Chloride 3 M in THF be stored to optimize its stability?

A: Storage should be in a cool (28C), dry place under an inert atmosphere such as argon or nitrogen. Containers must remain sealed and protected from light, moisture, and air to prevent degradation and extend the products shelf life to approximately 12 months.

Q: What process is followed for using this reagent in methylation reactions?

A: Prior to use, ensure all apparatus and solvents are thoroughly dried. Introduce Methyl Magnesium Chloride in THF to the reaction vessel under inert gas. Carefully control addition to minimize exposure to moisture and ensure effective methylation of the substrate.

Q: What are the key benefits of using Methyl Magnesium Chloride 3 M in THF over other methylating agents?

A: Its high concentration, vigorous reactivity, and reliable methyl transfer under controlled conditions make it advantageous for producing a broad array of methylated compounds with precision, especially in the synthesis of complex pharmaceuticals and fine chemicals.

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