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Acenocoumarol

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MOQ : 50 Kilograms

Acenocoumarol Specification

Melting Point
185-187C

Ingredients
4-Hydroxy-3-(acetonyl) coumarin

Physical Form
Powder

Appearance
White to off-white crystalline powder

Purity
>99%

Molecular Formula
C19H15NO6

HS Code
29339900

EINECS No
205-825-2

Solubility
Slightly soluble in water; soluble in alcohol, acetone, and chloroform

Application
Used as an anticoagulant for the treatment and prevention of thromboembolic disorders

Molecular Weight
349.33 g/mol

Poisonous
YES

CAS No
152-72-7

Shelf Life
24 months

Product Type
Active Pharmaceutical Ingredient (API)

Smell
Odorless

Usage
For pharmaceutical formulations - oral anticoagulant therapy

Properties
Oral anticoagulant; vitamin K antagonist; white or off-white crystalline powder

Structural Formula
C19H15NO6

Storage
Store in a cool, dry place, protected from light

Shape
Crystalline

Grade
Pharmaceutical Grade

Taste
Bitter

Risk Codes
R28, R61, R68

Brand Names
Sintrom, Sinthrome

Boiling Point
Not applicable (decomposes)

Registration
DMF/CEP available upon request

Synonyms
Nicoumalone, Sintrom

Precautionary Statements
Handle with care, avoid inhalation and contact

Packaging
HDPE drums or customized as per requirement

Stability
Stable under recommended storage conditions

Therapeutic Category
Anticoagulant

Acenocoumarol Trade Information

Minimum Order Quantity
50 Kilograms

Supply Ability
1 Kilograms Per Week

Delivery Time
1 Week

About Acenocoumarol

Acenocoumarol

Other Name : (RS)-4-hydroxy-3-[1-(4-nitrophenyl)-3-oxobutyl]-2H-chromen-2-one
CAS Number : 152-72-7
Molecular Formula : C19H15NO6
Application : Anticoagulant agent: Vitamin K antagonist.

Pharmaceutical Application

Acenocoumarol is widely used in oral anticoagulant therapy to prevent and treat conditions caused by harmful blood clots, such as deep vein thrombosis and pulmonary embolism. Its efficacy makes it a popular choice for healthcare providers needing a reliable vitamin K antagonist.

Handling and Safety

Due to its toxic nature, Acenocoumarol must be handled with meticulous care. Avoid inhalation and contact with skin or eyes. Always use appropriate personal protective equipment and refer to its Risk Codes (R28, R61, R68) for additional precautions when working with this compound.

Quality and Storage

This product boasts a purity above 99% and complies with pharmaceutical-grade standards. Acenocoumarol should be stored in tightly sealed containers, away from direct sunlight and moisture, ensuring its stability and maintaining a shelf life of 24 months.

FAQs of Acenocoumarol:

Q: How is Acenocoumarol used in pharmaceutical formulations?

A: Acenocoumarol is administered orally in the form of tablets, primarily for anticoagulant therapy to reduce the risk of thromboembolic disorders. Its dosage is closely monitored by healthcare professionals to achieve the desired therapeutic effect while minimizing the risk of bleeding.

Q: What precautions should be taken when handling Acenocoumarol?

A: Because Acenocoumarol is poisonous, it should be handled with appropriate safety gear, such as gloves and masks. Avoid inhalation, ingestion, or contact with skin and eyes. Handle the powder in well-ventilated spaces and follow all recommended safety procedures.

Q: When should Acenocoumarol be used?

A: Acenocoumarol is used under medical supervision for the treatment and prevention of blood clots, such as in patients who have experienced deep vein thrombosis or are at risk of embolism. Therapy is individualized based on patient needs and frequent blood tests.

Q: Where should Acenocoumarol be stored to maintain its efficacy?

A: The compound should be stored in a cool, dry place, protected from direct light and moisture. Proper storage in its original packaging, such as HDPE drums, ensures a stable environment and extends its shelf life to 24 months.

Q: What is the benefit of using Acenocoumarol as an anticoagulant?

A: The chief benefit of Acenocoumarol lies in its effectiveness as a vitamin K antagonist, helping to prevent and treat dangerous clotting disorders. This action can be life-saving for patients prone to thromboembolic conditions.

Q: What is the process for obtaining regulatory documentation for Acenocoumarol?

A: Drug Master File (DMF) and Certificate of Suitability to the Monographs of the European Pharmacopoeia (CEP) are available for Acenocoumarol upon request, making it suitable for international distribution and compliance.

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