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Di-Tert-butyl Dicarbonate(DiBOC)

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MOQ : 1 Liter

Di-Tert-butyl Dicarbonate(DiBOC) Specification

Storage
Store in a cool, dry and well-ventilated place, tightly closed

Moisture (%)
0.2%

Grade
Industrial Grade

Molecular Formula
C10H18O5

Water Solubility
Low (Slightly soluble in water, soluble in organic solvents)

Ph Level
Neutral

Heavy Metal (%)
0.001%

Shelf Life
2 Years

Smell
Odorless

Structural Formula
(CH3)3COCO2OC(CH3)3

Molecular Weight
218.25 g/mol

HS Code
29209010

Assay
>=99%

EINECS No
246-448-1

Loss on Drying
0.5%

Chemical Name
Di-Tert-butyl Dicarbonate (DiBOC)

CAS No
24424-99-5

Usage
Used as a protecting agent for amines in organic synthesis

Purity(%)
99%

Appearance
White crystalline powder

Application
Widely used in pharmaceuticals, peptide synthesis, and fine chemical industries

Packaging
Available in 25kg fiber drum or as per customer requirement

Stability
Stable under recommended storage conditions

Flash Point
90°C (closed cup)

Boiling Point
51-53°C (at 0.5 mmHg)

Transportation
Non-hazardous chemicals, handle with care

Refractive Index
n20/D 1.412

Melting Point
22-24°C

Density
1.1 g/cm³ (at 25°C)

Incompatibility
Strong acids, bases, and oxidizing agents

About Di-Tert-butyl Dicarbonate(DiBOC)

Di-Tert-butyl Dicarbonate(DiBOC)

CAS No.: 24424-99-5

Appearance : Colorless liquid & white crystalline solid

Assay : 99 min %

Specific Gravity : 0.95

Melting Point °C : 22~24

Boiling Point °C : 56~57

Flash point °C : 37

Application : For manufacturing of medical and organic intermediates, an important amino protective agent (Peptides).

Key Features and Specifications

DiBOC boasts a purity of at least 99%, a low loss on drying (0.5%), and minimal heavy metal content (0.001%). Its density is 1.1 g/cm at 25C, while its flash point stands at 90C, ensuring safe handling. The product remains stable when stored in a cool, dry, and well-ventilated environment, tightly sealed, maintaining a shelf life of up to two years.

Applications and Benefits

As an essential reagent in organic synthesis, DiBOC provides efficient protection of amine groups, facilitating intricate chemical reactions. Its use is prevalent in pharmaceutical production, peptide synthesis, and the creation of fine chemicals. The reliability and quality of DiBOC contribute to enhanced yield and process safety for researchers and manufacturers alike.

FAQs of Di-Tert-butyl Dicarbonate(DiBOC):

Q: How should Di-Tert-butyl Dicarbonate (DiBOC) be stored to ensure its stability?

A: DiBOC should be stored in a cool, dry, and well-ventilated location, with the container tightly sealed. Proper storage conditions help maintain its stability and extend its shelf life up to two years.

Q: What is the main usage of DiBOC in industrial applications?

A: DiBOC is primarily used as a protecting agent for amines in organic synthesis, making it valuable in pharmaceuticals, peptide synthesis, and fine chemical manufacturing processes.

Q: When handling DiBOC, what precautions should be observed during transportation?

A: Although classified as a non-hazardous chemical, DiBOC should be handled with care during transportation to avoid contact with incompatible substances such as strong acids, bases, and oxidizing agents, ensuring the safety of handlers and the integrity of the material.

Q: Where can DiBOC be purchased, and what packaging options are available?

A: DiBOC is readily available throughout India from distributors, exporters, importers, manufacturers, retailers, suppliers, traders, and wholesalers. Common packaging includes 25kg fiber drums or customized packaging as per customer requirements.

Q: What benefits does DiBOC provide in pharmaceutical and peptide synthesis processes?

A: DiBOC enhances process efficiency by reliably protecting amine groups, enabling more precise and controlled chemical reactions. Its high purity and stability contribute to improved safety, yield, and product quality.

Q: Is DiBOC soluble in water or organic solvents?

A: DiBOC is only slightly soluble in water but dissolves efficiently in organic solvents, supporting its application in various organic synthesis procedures.

Q: What is the recommended process for using DiBOC as a protecting agent in organic synthesis?

A: To use DiBOC as a protecting agent, combine it with the desired amine under controlled laboratory conditions, typically requiring mild bases or solvents. The process yields protected amines suitable for further chemical transformations without unwanted side reactions.

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