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Highly Soluble in Water L-Glutamic Acid Mono Sodium Salt 99% Extra Pure
Highly Soluble in Water L-Glutamic Acid Mono Sodium Salt 99% Extra Pure
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Highly Soluble in Water L-Glutamic Acid Mono Sodium Salt 99% Extra Pure

Price 1250.0 INR/ Kilograms

Get a Price/Quote
MOQ : 1 Kilograms

Highly Soluble in Water L-Glutamic Acid Mono Sodium Salt 99% Extra Pure Specification

  • Poisonous
  • No
  • Other Names
  • Monosodium Glutamate (MSG)
  • Ph Level
  • 6.7 - 7.2 (5% solution)
  • Solubility
  • Highly soluble in water
  • Boiling point
  • Decomposes before boiling
  • Molecular Weight
  • 169.11 g/mol
  • Melting Point
  • 232 C (decomposes)
  • Storage
  • Other
  • Molecular Formula
  • C5H8NO4Na
  • Shape
  • Crystalline Powder
  • HS Code
  • 2922.42.10
  • Purity
  • 99%
  • Structural Formula
  • HOOC-(CH2)2-CH(NH2)-COONa
  • Form
  • Solid
  • Smell
  • Other
  • Taste
  • Other
  • Density
  • 1.62 Gram per cubic centimeter(g/cm3)
  • Classification
  • Other
  • Chemical Name
  • L-Glutamic Acid Mono Sodium Salt
  • CAS No
  • 142-47-2
  • EINECS No
  • 205-538-1
  • Grade
  • Other
  • Standard
  • 99%
  • Type
  • Powder
  • Usage
  • Used as a flavor enhancer in food and also as a dietary supplement
  • Main Material
  • L-Glutamic Acid
  • Application
  • Other
 

Highly Soluble in Water L-Glutamic Acid Mono Sodium Salt 99% Extra Pure Trade Information

  • Minimum Order Quantity
  • 1 Kilograms
  • Sample Available
  • No
 

About Highly Soluble in Water L-Glutamic Acid Mono Sodium Salt 99% Extra Pure


Tubulysin A

CAS Number: 253392-12-8

Molecular Formula: CHNO

Molecular Weight: 646.81 g/mol

Appearance: White to off-white solid / powder

Purity (HPLC):  95%


Tubulysin A is one of the most studied members of the tubulysin family a group of highly cytotoxic natural products known for their potent anti-mitotic activity. These compounds are isolated from myxobacteria such as Archangium gephyra and Angiococcus disciformis.

 Tubulysin A Overview
Feature Details
Class Tetrapeptide cytotoxin
Source Myxobacteria
Mechanism Microtubule depolymerization
Potency Extremely high (picomolar range)
Use Research tool, payload in ADCs
 Chemical Structure

Tubulysin A is a tetrapeptide made up of:

  1. N-Methylpipecolic acid (Mep)

  2. Isoleucine (or a variant)

  3. Tubuvaline (Tuv)  Contains a thiazole and a methylated hydroxyl group

  4. Tubutyrosine (Tut)  A highly modified tyrosine residue

These unusual building blocks give Tubulysin A its:

  • Hydrophobic character

  • High binding affinity to tubulin

  • Resistance to proteolysis

 Mechanism of Action

  • Binds to tubulin and inhibits microtubule polymerization

  • Causes mitotic arrest in the G2/M phase

  • Triggers apoptosis through mitochondrial pathways

It works similarly to agents like vinblastine, but is 1001000 more potent.

Therapeutic Relevance

Tubulysin A is too toxic for direct systemic use, but:

  • It is used in Antibody-Drug Conjugates (ADCs) as a cytotoxic payload

  • Derivatives and synthetic analogs are being developed for targeted cancer therapy

  • Notable for its effectiveness against drug-resistant cancer cells

Biosynthesis


  • Synthesized by non-ribosomal peptide synthetases (NRPS) and polyketide synthase (PKS) hybrid systems

  • The complex biosynthetic gene cluster encodes tailoring enzymes for methylation, oxidation, and cyclization


Highly Soluble in Water L-Glutamic Acid Mono Sodium Salt 99% Extra Pure
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