Highly Soluble in Water L-Glutamic Acid Mono Sodium Salt 99% Extra Pure

1250.0 INR/Kilograms

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Product Details:

Smell Other
Taste Other
Molecular Formula C5H8NO4Na
Molecular Weight 169.11 g/mol
Boiling point Decomposes before boiling
Density 1.62 Gram per cubic centimeter(g/cm3)
Form Solid
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Highly Soluble in Water L-Glutamic Acid Mono Sodium Salt 99% Extra Pure Price And Quantity

Minimum Order Quantity 1 Kilograms
Price 1250.0 INR/Kilograms

Highly Soluble in Water L-Glutamic Acid Mono Sodium Salt 99% Extra Pure Product Specifications

Chemical Name L-Glutamic Acid Mono Sodium Salt
HS Code 2922.42.10
Type Powder
Solubility Highly soluble in water
Classification Other
Purity 99%
Ph Level 6.7 - 7.2 (5% solution)
Application Other
Shape Crystalline Powder
EINECS No 205-538-1
Melting Point 232 C (decomposes)
Usage Used as a flavor enhancer in food and also as a dietary supplement
Structural Formula HOOC-(CH2)2-CH(NH2)-COONa
CAS No 142-47-2
Storage Other
Other Names Monosodium Glutamate (MSG)
Main Material L-Glutamic Acid
Grade Other
Form Solid
Poisonous Non-toxic when used as directed
Standard 99%
Molecular Formula C5H8NO4Na
Taste Other
Smell Other
Density 1.62 Gram per cubic centimeter(g/cm3)
Boiling point Decomposes before boiling
Molecular Weight 169.11 g/mol

Highly Soluble in Water L-Glutamic Acid Mono Sodium Salt 99% Extra Pure Trade Information

Sample Available Yes

Product Description

Tubulysin A

CAS Number: 253392-12-8

Molecular Formula: CHNO

Molecular Weight: 646.81 g/mol

Appearance: White to off-white solid / powder

Purity (HPLC): 95%

Tubulysin A is one of the most studied members of the tubulysin family a group of highly cytotoxic natural products known for their potent anti-mitotic activity. These compounds are isolated from myxobacteria such as Archangium gephyra and Angiococcus disciformis.

Tubulysin A Overview

Feature	Details
Class	Tetrapeptide cytotoxin
Source	Myxobacteria
Mechanism	Microtubule depolymerization
Potency	Extremely high (picomolar range)
Use	Research tool, payload in ADCs

Chemical Structure

Tubulysin A is a tetrapeptide made up of:

N-Methylpipecolic acid (Mep)
Isoleucine (or a variant)
Tubuvaline (Tuv) Contains a thiazole and a methylated hydroxyl group
Tubutyrosine (Tut) A highly modified tyrosine residue

These unusual building blocks give Tubulysin A its:

Hydrophobic character
High binding affinity to tubulin
Resistance to proteolysis

Mechanism of Action

Binds to tubulin and inhibits microtubule polymerization
Causes mitotic arrest in the G2/M phase
Triggers apoptosis through mitochondrial pathways

It works similarly to agents like vinblastine, but is ~1001000 more potent.

Therapeutic Relevance

Tubulysin A is too toxic for direct systemic use, but:

It is used in Antibody-Drug Conjugates (ADCs) as a cytotoxic payload
Derivatives and synthetic analogs are being developed for targeted cancer therapy
Notable for its effectiveness against drug-resistant cancer cells

Biosynthesis

Synthesized by non-ribosomal peptide synthetases (NRPS) and polyketide synthase (PKS) hybrid systems
The complex biosynthetic gene cluster encodes tailoring enzymes for methylation, oxidation, and cyclization

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